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      Prevalence of HBV infection in immunocompromised patients on ART nearly equals HBV mono infection in individuals not infected with HIV, Shimla Northern India

      , 1 , 1 , 1 , 1 , 1 , 1

      BMC Infectious Diseases

      BioMed Central

      2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014)

      30 January-1 February 2014

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          Background It is estimated that 5% of the global population is chronically infected with HBV. The rate of HBV-HIV co infection is 10-20% in countries with HBV endemicity. The present study was undertaken to examine the HBV prevalence and HBV-HIV co infection at tertiary care institute, Northern India. Methods This is a retrospective study for the duration of five years, 2008-13. The HBV infection was detected using HBsAg (Hepatitis B surface antigen) and HIV/AIDS cases were screened as per NACO, 2007 criteria. Results A total of 10,134 cases were screened for detection of HBV infection and among these 1650(16.3%) were receiving ART (anti retroviral therapy) while HIV status was not divulged in 8484 (83.7%). HBsAg positive in 324/10134 (3.20%) cases, out of these HBV mono infection was seen in 264 (2.6%) and co- infection with HIV in 60 (0.6%).The concomitant HIV infections were seen in 3.64% (95 %confidence interval 2.8-4.7) while in HBV mono infections were in 3.1% (95 % confidence interval 2.8-3.4). There is no statistical difference among the two groups (p value >0.05). Among the pediatric age group 0.95% had concomitant HIV infections as against 5.2% with HBV infection alone. The mean age of presentation was 40.39 years. Males had higher prevalence rate of co infection (4.5:1). Conclusion Nearly identical prevalence of HBV infection irrespective of HIV infection strongly indicates HIV screening for Hepatitis B infected patients. The presence of undetected co infection shall result in missed cases, incomplete or partial treatment and suboptimal clinical follow up.

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          Author and article information

          [1 ]Indira Gandhi Medical College (IGMC), Shimla, Himachal Pradesh, India
          BMC Infect Dis
          BMC Infect. Dis
          BMC Infectious Diseases
          BioMed Central
          27 May 2014
          : 14
          : Suppl 3
          : P26
          Copyright © 2014 Garg et al; licensee BioMed Central Ltd.

          This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

          2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014)
          Chennai, India
          30 January-1 February 2014
          Poster Presentation

          Infectious disease & Microbiology


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