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      Astrobiology in Space: A Comprehensive Look at the Solar System

      Life
      MDPI AG

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          Abstract

          The field of astrobiology aims to understand the origin of life on Earth and searches for evidence of life beyond our planet. Although there is agreement on some of the requirements for life on Earth, the exact process by which life emerged from prebiotic conditions is still uncertain, leading to various theories. In order to expand our knowledge of life and our place in the universe, scientists look for signs of life through the use of biosignatures, observations that suggest the presence of past or present life. These biosignatures often require up-close investigation by orbiters and landers, which have been employed in various space missions. Mars, because of its proximity and Earth-like environment, has received the most attention and has been explored using (sub)surface sampling and analysis. Despite its inhospitable surface conditions, Venus has also been the subject of space missions due to the presence of potentially habitable conditions in its atmosphere. In addition, the discovery of habitable environments on icy moons has sparked interest in further study. This article provides an overview of the origin of life on Earth and the astrobiology studies carried out by orbiters and landers.

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          Most cited references46

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          Design and synthesis of a minimal bacterial genome.

          We used whole-genome design and complete chemical synthesis to minimize the 1079-kilobase pair synthetic genome of Mycoplasma mycoides JCVI-syn1.0. An initial design, based on collective knowledge of molecular biology combined with limited transposon mutagenesis data, failed to produce a viable cell. Improved transposon mutagenesis methods revealed a class of quasi-essential genes that are needed for robust growth, explaining the failure of our initial design. Three cycles of design, synthesis, and testing, with retention of quasi-essential genes, produced JCVI-syn3.0 (531 kilobase pairs, 473 genes), which has a genome smaller than that of any autonomously replicating cell found in nature. JCVI-syn3.0 retains almost all genes involved in the synthesis and processing of macromolecules. Unexpectedly, it also contains 149 genes with unknown biological functions. JCVI-syn3.0 is a versatile platform for investigating the core functions of life and for exploring whole-genome design.
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            A Production of Amino Acids Under Possible Primitive Earth Conditions

            S Miller (1953)
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              Cometary glycine detected in samples returned by Stardust

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                Author and article information

                Contributors
                (View ORCID Profile)
                Journal
                LBSIB7
                Life
                Life
                MDPI AG
                2075-1729
                March 2023
                March 01 2023
                : 13
                : 3
                : 675
                Article
                10.3390/life13030675
                881269fc-f472-4a34-84b3-36fdbe31fed6
                © 2023

                https://creativecommons.org/licenses/by/4.0/

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