13
views
0
recommends
+1 Recommend
2 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Evaluation of Fetomaternal Outcome in Advanced Age-group Mothers: A Comparative Prospective Study in a Tertiary Care Maternity Hospital in Kashmir Valley

      research-article

      Read this article at

      ScienceOpenPublisher
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          ABSTRACT

          Aim

          The study was aimed to investigate the effect of maternal age on fetomaternal outcomes in primigravida singleton women aged above 35 years vs the younger age-group of 22–35 years.

          Materials and methods

          The study was carried out for a period of 18 months in the Department of Obstetrics and Gynaecology, Government Medical College, Srinagar, Jammu and Kashmir, India. The data were prospectively collected on 209 primigravida singleton pregnant women admitted to the hospital and were divided into two groups, one above 35 years and the other between 22 and 35 years. The fetomaternal outcome of each pregnancy was recorded and exported on the data editor of Statistical Package for the Social Sciences (SPSS) version 20.0. The comparative analysis between the two groups was done using the Student's independent t-test or Mann–Whitney U test.

          Results

          Comparative analysis between two groups of primigravida singleton pregnant women showed that advanced-age pregnancy was significantly associated with increased incidence of gestational hypertension (38.6 vs 22.4%, p = 0.018), antepartum hemorrhage (APH) (21.1 vs 9.9, p = 0.031), spontaneous abortions (17.5 vs 7.2%, p = 0.027%), and cesarean delivery rate (64.3 vs 46.3, p = 0.042) as compared to younger age-group.

          Advanced-age pregnancy was associated with adverse fetal outcomes like low birth weight (26.2 vs 13.2%, p = 0.047), preterm delivery (38.1 vs 22.1%, p = 0.029), intrauterine fetal demise (IUFD) (16.7 vs 6.6%, p = 0.047), and intrauterine growth retardation (IUGR) (33.3 vs 16.21%, p = 0.016) as compared with younger age-group.

          Conclusion

          This study shows a strong association of advanced maternal age with adverse fetomaternal outcomes, and the rising trend of delaying pregnancy makes it imperative to educate women about the risks of advanced-age pregnancy and the need for specialized care during the antenatal period.

          How to cite this article

          Manzoor S, Rizvi SM. Evaluation of Fetomaternal Outcome in Advanced Age-group Mothers: A Comparative Prospective Study in a Tertiary Care Maternity Hospital in Kashmir Valley. Int J Infertil Fetal Med 2023;14(2):94-99.

          Related collections

          Most cited references37

          • Record: found
          • Abstract: found
          • Article: not found

          Pregnancy-Related Mortality in the United States, 2011–2013

          To update national population-level pregnancy-related mortality estimates and examine characteristics and causes of pregnancy-related deaths in the United States during 2011-2013.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: found
            Is Open Access

            Role of maternal age and pregnancy history in risk of miscarriage: prospective register based study

            Abstract Objectives To estimate the burden of miscarriage in the Norwegian population and to evaluate the associations with maternal age and pregnancy history. Design Prospective register based study. Setting Medical Birth Register of Norway, the Norwegian Patient Register, and the induced abortion register. Participants All Norwegian women that were pregnant between 2009-13. Main outcome measure Risk of miscarriage according to the woman’s age and pregnancy history estimated by logistic regression. Results There were 421 201 pregnancies during the study period. The risk of miscarriage was lowest in women aged 25-29 (10%), and rose rapidly after age 30, reaching 53% in women aged 45 and over. There was a strong recurrence risk of miscarriage, with age adjusted odds ratios of 1.54 (95% confidence interval 1.48 to 1.60) after one miscarriage, 2.21 (2.03 to 2.41) after two, and 3.97 (3.29 to 4.78) after three consecutive miscarriages. The risk of miscarriage was modestly increased if the previous birth ended in a preterm delivery (adjusted odds ratio 1.22, 95% confidence interval 1.12 to 1.29), stillbirth (1.30, 1.11 to 1.53), caesarean section (1.16, 1.12 to 1.21), or if the woman had gestational diabetes in the previous pregnancy (1.19, 1.05 to 1.36). The risk of miscarriage was slightly higher in women who themselves had been small for gestational age (1.08, 1.04 to 1.13). Conclusions The risk of miscarriage varies greatly with maternal age, shows a strong pattern of recurrence, and is also increased after some adverse pregnancy outcomes. Miscarriage and other pregnancy complications might share underlying causes, which could be biological conditions or unmeasured common risk factors.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Advanced maternal age and adverse perinatal outcome.

              The aim of this study was to investigate the influence of maternal age on perinatal and obstetric outcome in women aged 40-44 years and those 45 years or older and to estimate whether adverse outcome was related to intercurrent illness and pregnancy complications. National prospective, population-based, cohort study in women aged 40-44 years and those 45 years or older and in a control group of women aged 20-29 years who delivered during the period 1987-2001. Adjusted odds ratios (OR) were calculated after adjustments for significant malformations, maternal pre-existing diseases, and smoking. Main outcome measures were perinatal mortality, intrauterine fetal death, neonatal death, preterm birth, and preeclampsia. During the 15-year period, there were 1,566,313 deliveries (876,361 women were 20-29 years of age, 31,662 were 40-44 years, and 1,205 were > or = 45 years). Perinatal mortality was 1.4%, 1.0%, and 0.5% in women 45 years or older, 40-44, and 20-29 years, respectively. Adjusted OR for perinatal mortality was 2.4 (95% confidence interval [CI] 1.5-4.0) in women aged 45 years or older, compared with 1.7 (95% CI 1.5-1.9) in women 40-44 years. Adjusted OR for intrauterine fetal death was 3.8 (95% CI 2.2-6.4) in women aged 45 years or older, compared with 2.1 (95% CI 1.8-2.4) in women 40-44 years. Preterm birth, gestational diabetes, and preeclampsia were more common among women 40-44 years of age and those 45 years or older. Perinatal mortality was increased in women with intercurrent illness or pregnancy complications compared with women without these conditions, but there was no evidence that these factors became more important with increasing age. Perinatal mortality, intrauterine fetal death, and neonatal death increased with age. There was also an increase in intercurrent illnesses and pregnancy complications with increasing age, but this did not entirely explain the observed increase in perinatal mortality with age. II-3
                Bookmark

                Author and article information

                Journal
                IJIFM
                International Journal of Infertility and Fetal Medicine
                IJIFM
                Jaypee Brothers Medical Publishers
                2229-3817
                2229-3833
                May-August 2023
                : 14
                : 2
                : 94-99
                Affiliations
                [1,2 ]Department of Obstetrics and Gynaecology, Government Medical College, Srinagar, Jammu and Kashmir, India
                Author notes
                Shumila Manzoor, Department of Obstetrics and Gynaecology, Government Medical College, Srinagar, Jammu and Kashmir, India, Phone: +91 8899566147, e-mail: shumila.manzoor11@ 123456gmail.com
                Article
                10.5005/jp-journals-10016-1316
                88c45bb5-f0a3-4fc2-9232-d9f43c0c2ee4
                Copyright © 2023; The Author(s).

                © The Author(s). 2023 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 14 February 2023
                : 27 March 2023
                : 12 May 2023
                Categories
                RESEARCH ARTICLE
                Custom metadata
                ijifm-14-094.pdf

                Obstetrics & Gynecology
                Fetomaternal,Advanced age,Pregnancy,Risks,Adverse
                Obstetrics & Gynecology
                Fetomaternal, Advanced age, Pregnancy, Risks, Adverse

                Comments

                Comment on this article