11
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Low‐field MRI: Clinical promise and challenges

      review-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Modern MRI scanners have trended toward higher field strengths to maximize signal and resolution while minimizing scan time. However, high‐field devices remain expensive to install and operate, making them scarce outside of high‐income countries and major population centers. Low‐field strength scanners have drawn renewed academic, industry, and philanthropic interest due to advantages that could dramatically increase imaging access, including lower cost and portability. Nevertheless, low‐field MRI still faces inherent limitations in image quality that come with decreased signal. In this article, we review advantages and disadvantages of low‐field MRI scanners, describe hardware and software innovations that accentuate advantages and mitigate disadvantages, and consider clinical applications for a new generation of low‐field devices. In our review, we explore how these devices are being or could be used for high acuity brain imaging, outpatient neuroimaging, MRI‐guided procedures, pediatric imaging, and musculoskeletal imaging. Challenges for their successful clinical translation include selecting and validating appropriate use cases, integrating with standards of care in high resource settings, expanding options with actionable information in low resource settings, and facilitating health care providers and clinical practice in new ways. By embracing both the promise and challenges of low‐field MRI, clinicians and researchers have an opportunity to transform medical care for patients around the world.

          Level of Evidence

          5

          Technical Efficacy

          Stage 6

          Related collections

          Most cited references196

          • Record: found
          • Abstract: found
          • Article: not found

          Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct

          The effect of endovascular thrombectomy that is performed more than 6 hours after the onset of ischemic stroke is uncertain. Patients with a clinical deficit that is disproportionately severe relative to the infarct volume may benefit from late thrombectomy.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

            New England Journal of Medicine, 378(8), 708-718
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Global Burden of Stroke.

              On the basis of the GBD (Global Burden of Disease) 2013 Study, this article provides an overview of the global, regional, and country-specific burden of stroke by sex and age groups, including trends in stroke burden from 1990 to 2013, and outlines recommended measures to reduce stroke burden. It shows that although stroke incidence, prevalence, mortality, and disability-adjusted life-years rates tend to decline from 1990 to 2013, the overall stroke burden in terms of absolute number of people affected by, or who remained disabled from, stroke has increased across the globe in both men and women of all ages. This provides a strong argument that "business as usual" for primary stroke prevention is not sufficiently effective. Although prevention of stroke is a complex medical and political issue, there is strong evidence that substantial prevention of stroke is feasible in practice. The need to scale-up the primary prevention actions is urgent.
                Bookmark

                Author and article information

                Contributors
                tcarnold@seas.upenn.edu
                joel.stein@pennmedicine.upenn.edu
                Journal
                J Magn Reson Imaging
                J Magn Reson Imaging
                10.1002/(ISSN)1522-2586
                JMRI
                Journal of Magnetic Resonance Imaging
                John Wiley & Sons, Inc. (Hoboken, USA )
                1053-1807
                1522-2586
                19 September 2022
                January 2023
                : 57
                : 1 ( doiID: 10.1002/jmri.v57.1 )
                : 25-44
                Affiliations
                [ 1 ] Department of Bioengineering, School of Engineering & Applied Science University of Pennsylvania Philadelphia Pennsylvania USA
                [ 2 ] Center for Neuroengineering and Therapeutics University of Pennsylvania Philadelphia Pennsylvania USA
                [ 3 ] Department of Radiology, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA
                [ 4 ] Department of Neurology, Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania USA
                Author notes
                [*] [* ] Address reprint requests to: T.C.A., 240 Skirkanich Hall, 210 S 33rd St, Philadelphia, PA 19104, USA. E‐mail: tcarnold@ 123456seas.upenn.edu , or J.M.S., Hospital of the University of Pennsylvania, 1 Silverstein Pavilion, 3400 Spruce St., Philadelphia, PA 19104‐4283, USA. E‐mail: joel.stein@ 123456pennmedicine.upenn.edu

                Author information
                https://orcid.org/0000-0001-8226-8497
                https://orcid.org/0000-0002-0741-1780
                Article
                JMRI28408
                10.1002/jmri.28408
                9771987
                36120962
                8d5fb985-9926-405b-b4ef-22183bebf7e8
                © 2022 The Authors. Journal of Magnetic Resonance Imaging published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 11 August 2022
                : 05 June 2022
                : 12 August 2022
                Page count
                Figures: 9, Tables: 6, Pages: 20, Words: 15685
                Funding
                Funded by: Hyperfine, Inc.
                Funded by: National Institute of Biomedical Imaging and Bioengineering , doi 10.13039/100000070;
                Award ID: 5T32EB009384
                Funded by: Trustees of the University of Pennsylvania
                Funded by: National Institute of Neurological Disorders and Stroke , doi 10.13039/100000065;
                Award ID: R56‐NS099348
                Award ID: DP1‐NS122038
                Award ID: T32‐NS091006
                Funded by: Pennsylvania Health Research Formula Fund
                Funded by: Mirowski Family Fund
                Funded by: Jonathan Rothberg Family Fund
                Funded by: Neil and Barbara Smit
                Categories
                Review
                Reviews
                Custom metadata
                2.0
                January 2023
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.2.7 mode:remove_FC converted:11.04.2023

                Radiology & Imaging
                low‐field mri,portable mri,point‐of‐care mri,mri accessibility,healthcare cost,clinical low‐field mri

                Comments

                Comment on this article