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      Eco-Friendly Synthesis of a New Class of Pyridinium-Based Ionic Liquids with Attractive Antimicrobial Activity

      Molecules

      MDPI

      eco-friendly synthesis, ultrasound irradiation, ionic liquid, antimicrobial activity

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          Abstract

          The present study reports a green synthesis of a new family of ionic liquids (ILs) based on functionalized 4-dimethylaminopyridinium derivatives. The structures of 23 newly synthesized ILs ( 224) were confirmed by FT-IR, 1H-, 13C-, 11B-, 19F-, and 31P-NMR spectroscopy and mass spectrometry. The antimicrobial activity of all novel ILs was tested against a panel of bacteria and fungi. The results prove that all tested ILs are effective antibacterial and antifungal agents, especially 4-(dimethylamino)-1-(4-phenoxybutyl)pyridinium derivatives 5 and 19.

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          Most cited references 28

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          Non-haloaluminate room-temperature ionic liquids in electrochemistry--a review.

          Some twenty-five years after they first came to prominence as alternative electrochemical solvents, room temperature ionic liquids (RTILs) are currently being employed across an increasingly wide range of chemical fields. This review examines the current state of ionic liquid-based electrochemistry, with particular focus on the work of the last decade. Being composed entirely of ions and possesing wide electrochemical windows (often in excess of 5 volts), it is not difficult to see why these compounds are seen by electrochemists as attractive potential solvents. Accordingly, an examination of the pertinent properties of ionic liquids is presented, followed by an assessment of their application to date across the various electrochemical disciplines, concluding with an outlook viewing current problems and directions.
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            Toxicity and antimicrobial activity of imidazolium and pyridinium ionic liquids

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              Ionic liquids: solvents for the electrodeposition of metals and semiconductors

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                Author and article information

                Contributors
                Role: Academic Editor
                Journal
                Molecules
                Molecules
                molecules
                Molecules
                MDPI
                1420-3049
                14 August 2015
                August 2015
                : 20
                : 8
                : 14936-14949
                Affiliations
                Department of Chemistry, Taibah University, Al-Madina Al-Mounawara 30002, Saudi Arabia; E-Mail: mouslim@ 123456mail.be ; Tel.: +966-562-441-572
                Article
                molecules-20-14936
                10.3390/molecules200814936
                6331848
                26287148
                © 2015 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license ( http://creativecommons.org/licenses/by/4.0/).

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