Non-linear associations between serum 25-OH vitamin D and indices of arterial stiffness and arteriosclerosis in an older population.

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Abstract

several studies have been pointing towards a non-linear relationship between serum 25(OH)D and cardiovascular disease. Next to vitamin D deficiency, also higher levels of 25(OH)D have been reported to be associated with increased cardiovascular risk. We aimed to investigate the nature of the relationship between serum 25(OH)D and measures of arterial stiffness and arteriosclerosis in an elderly population.

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Journal

Journal ID (iso-abbrev): Age Ageing

Title: Age and ageing

ISSN (Electronic): 1468-2834

ISSN (Print): 0002-0729

Publication date (Electronic): Jan 2015

Volume: 44

Issue: 1

Affiliations

[1 ] Department of Geriatrics, Erasmus MC,'s Gravendijkwal 230, Rotterdam 3015 CE, The Netherlands.

[2 ] Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.

[3 ] Department of Internal Medicine, Section of Geriatrics, Erasmus MC, PO Box 2040, Rotterdam 3000 CA, The Netherlands.

[4 ] Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands.

[5 ] Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands Netherlands Consortium for Healthy Aging, Rotterdam, Leiden, The Netherlands.

[6 ] Wageningen University, Wageningen, The Netherlands.

[7 ] Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands.

[8 ] Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands.

[9 ] Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands Institute for Cardiovascular Research ICaR-VU, VU University Medical Center, Amsterdam, The Netherlands.

[10 ] Department of Geriatrics, Erasmus MC,'s Gravendijkwal 230, Rotterdam 3015 CE, The Netherlands Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands.

[11 ] Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands Department of Internal Medicine, Endocrine Section & EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.

[12 ] Department of Vascular Medicine, Erasmus MC, Rotterdam, The Netherlands.

[13 ] Department of Geriatric Medicine, Erasmus MC, PO Box 2040, Rotterdam 3000 CA, The Netherlands.

Article

Publisher Item ID: afu095

DOI: 10.1093/ageing/afu095

PubMed ID: 25038832

SO-VID: 8f7911a4-9fe4-40db-8f6e-fd8ea91e7ef6

History

Keywords: arterial stiffness,arteriosclerosis,non-linear associations,older people,serum 25-OH vitamin D

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Keywords: arterial stiffness, arteriosclerosis, non-linear associations, older people, serum 25-OH vitamin D

Non-linear associations between serum 25-OH vitamin D and indices of arterial stiffness and arteriosclerosis in an older population.

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