For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
13
views
21
references
 Top references
cited by
3
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      91
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Pulmonary Nocardiosis and Scrub Typhus in an Immunocompromised Host

      case-report

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Pulmonary infections are not uncommon in patients with an underlying immunocompromised condition. Unusual combination of microorganisms causing concomitant infections among these patients has also been reported. However, certain rare dual occurrences are usually unanticipated as in the case we present here. This case highlights the importance of being aware of the possible coexistence of infections in immunocompromised patients. To the best of our knowledge, this is the first report of coinfection with Nocardia otitidiscaviarum and Orientia tsutsugamushi in a critically ill immunocompromised patient from South India.

          Related collections

          Most cited references21

          • Record: found
          • Abstract: found
          • Article: not found

          Nocardiosis: updates and clinical overview.

          John W Wilson (2012)
          Nocardia, a gram-positive bacillus with the microscopic appearance of branching hyphae, can produce considerable disease in the appropriate host. The taxonomy of Nocardia continues to evolve; more than 50 species have been described. Early recognition and effective therapy are imperative to achieve successful outcomes. Although nocardiosis typically occurs in patients with cell-mediated immunosuppressive conditions, infection may occasionally develop in immunocompetent patients as well. This review addresses the microbiology of Nocardia, risk factors for infection, clinical presentations, and management strategies. Copyright © 2012 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
          Article 0 comments Cited 218 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Antimicrobial-resistant nocardia isolates, United States, 1995-2004.

            Kristin Broome Uhde, Sonal Pathak, Isaac McCullum … (2010)
            We conducted a 10-year retrospective evaluation of the epidemiology and identification of Nocardia isolates submitted to the Centers for Disease Control and Prevention for antimicrobial susceptibility testing. The species most commonly identified were N. nova (28%), N. brasiliensis (14%), and N. farcinica (14%). Of 765 isolates submitted, 61% were resistant to sulfamethoxazole and 42% were resistant to trimethoprim-sulfamethoxazole.
            Article 0 comments Cited 64 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              Scrub typhus

              Amy Rapsang, Prithwis Bhattacharyya (2013)
              Scrub typhus is an acute febrile illness caused by orientia tsutsugamushi, transmitted to humans by the bite of the larva of trombiculid mites. It causes a disseminated vasculitic and perivascular inflammatory lesions resulting in significant vascular leakage and end-organ injury. It affects people of all ages and even though scrub typhus in pregnancy is uncommon, it is associated with increased foetal loss, preterm delivery, and small for gestational age infants. After an incubation period of 6-21 days, onset is characterized by fever, headache, myalgia, cough, and gastrointestinal symptoms. A primary papular lesion which later crusts to form a flat black eschar, may be present. If untreated, serious complications may occur involving various organs. Laboratory studies usually reveal leukopenia, thrombocytopenia, deranged hepatic and renal function, proteinuria and reticulonodular infiltrate. Owing to the potential for severe complications, diagnosis, and decision to initiate treatment should be based on clinical suspicion and confirmed by serologic tests. A therapeutic trial of tetracycline or chloramphenicol is indicated in patients in whom the diagnosis of scrub typhus is suspected. The recommended treatment regimen for scrub typhus is doxycycline. Alternative regimens include tetracycline, chloramphenicol, azithromycin, ciprofloxacin, rifampicin, and roxithromycin. Treatment of pregnant women with azithromycin was successfully done without relapse and with favorable pregnancy outcomes. Hence, early diagnosis and treatment are essential in order to reduce the mortality and the complications associated with the disease. We searched the English-language literature for reports of scrub typhus in children, pregnant women, and non-pregnant patients with scrub typhus, using the MEDLINE/PubMed database, which includes citations from 1945 to the present time. We used the search terms ‘scrub typhus’, ‘scrub typhus’ and ‘pregnancy’, ‘scrub typhus’ and ‘children’, ‘scrub typhus’ and ‘complications’, ‘scrub typhus’ and ‘treatment’.
              Article 0 comments Cited 19 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): J Glob Infect Dis
                Journal ID (iso-abbrev): J Glob Infect Dis
                Journal ID (publisher-id): JGID
                Title: Journal of Global Infectious Diseases
                Publisher: Medknow Publications & Media Pvt Ltd (India )
                ISSN (Print): 0974-777X
                ISSN (Electronic): 0974-8245
                Publication date (Print): Apr-Jun 2018
                Volume: 10
                Issue: 2
                Pages: 108-111
                Affiliations
                [1]Department of Microbiology, Apollo Speciality Hospitals, Vanagaram, Chennai, Tamil Nadu, India
                [1 ]Department of Critical Care Medicine, Apollo Speciality Hospitals, Vanagaram, Chennai, Tamil Nadu, India
                [2 ]Department of Critical Care Medicine, Apollo Hospitals, Greams Road, Chennai, Tamil Nadu, India
                [3 ]Department of Microbiology, Apollo Hospitals, Greams Road, Chennai, Tamil Nadu, India
                Author notes
                Address for correspondence: Dr. Isabella Princess, Apollo Speciality Hospitals, Vanagaram, Chennai, Tamil Nadu, India. E-mail: drisabella_p@ 123456apollohospitals.com
                Article
                Publisher ID: JGID-10-108
                DOI: 10.4103/jgid.jgid_105_17
                PMC ID: 5987364
                PubMed ID: 29910572
                SO-VID: 908d18f2-74e1-42e4-ab2a-799068397fc3
                Copyright © Copyright: © 2018 Journal of Global Infectious Diseases
                License:

                This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

                History
                Categories
                Subject: Case Report

                ScienceOpen disciplines: Infectious disease & Microbiology
                Keywords: coinfection,immunocompromised,nocardia otitidiscaviarum,nocardiosis,scrub typhus
                Data availability:
                ScienceOpen disciplines: Infectious disease & Microbiology
                Keywords: coinfection, immunocompromised, nocardia otitidiscaviarum, nocardiosis, scrub typhus

                Comments

                Comment on this article

                scite_

                Similar content91

                See all similar

                Cited by3

                See all cited by

                Most referenced authors144

                See all reference authors