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      Identification of Inhibitory and Stimulatory Control of Prolactin Secretion in the Rhesus Monkey

      research-article
      , ,
      Neuroendocrinology
      S. Karger AG
      Prolactin, LH, Pentobarbital, Pulsatile release, Rhesus monkey, Circhoral clock

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          Abstract

          In the unanesthetized, ovariectomized rhesus monkey, gonadotropin secretion is episodic while prolactin (Prl) release is relatively constant. Under pentobarbital anesthesia, however, Prl secretion also becomes pulsatile in synchrony with the discharges of LH. This finding suggests that the anesthesia has unmasked normally inhibited Prl releasing stimuli which are driven by the circhoral ‘clock’ that also times the discharges of GnRH.

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          Author and article information

          Journal
          NEN
          Neuroendocrinology
          10.1159/issn.0028-3835
          Neuroendocrinology
          S. Karger AG
          0028-3835
          1423-0194
          1978
          1978
          26 March 2008
          : 27
          : 1-2
          : 32-38
          Affiliations
          Department of Physiology, University of Pittsburgh, School of Medicine, Pittsburgh, Pa.
          Article
          122798 Neuroendocrinology 1978;27:32–38
          10.1159/000122798
          104185
          90ce2105-6662-48eb-987a-c7a0c1604e08
          © 1978 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 24 February 1978
          : 14 April 1978
          Page count
          Pages: 7
          Categories
          Paper

          Endocrinology & Diabetes,Neurology,Nutrition & Dietetics,Sexual medicine,Internal medicine,Pharmacology & Pharmaceutical medicine
          LH,Pulsatile release,Prolactin,Circhoral clock,Pentobarbital,Rhesus monkey

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