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      Amoxicillin vs third-generation cephalosporin for infection prophylaxis after third molar extraction.

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          Abstract

          Although amoxicillin is the first-line prophylactic drug for impacted mandibular third molar extraction, third-generation cephalosporins are widely prescribed in Japan. The lack of real-world evidence may be one reason for this inappropriate use. We evaluated differences in the incidence of surgical site infection between amoxicillin and third-generation cephalosporins for impacted mandibular third molar extraction.

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          Author and article information

          Journal
          Oral Dis
          Oral diseases
          Wiley
          1601-0825
          1354-523X
          Mar 2024
          : 30
          : 2
          Affiliations
          [1 ] Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
          [2 ] Department of Health Services Research, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
          [3 ] Department of Eat-loss Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
          [4 ] Department of Oral Health Promotion, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
          Article
          10.1111/odi.14421
          36321875
          968b0f94-aeed-4eac-b75a-61babb4b906a
          History

          tooth extraction,surgical site infection prophylaxis,propensity-score matching,impacted mandibular third molar,antimicrobial resistance

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