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      Frontal cutaneous meningioma - Case report*

      case-report

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          Abstract

          Cutaneous meningiomas are rare tumors most commonly located on the scalp. We report the case of a 55-year-old male who presented with a 2x3 cm tumoral lesion on the forehead. The lesion was hard, adherent and covered by normal skin. Incisional biopsy revelead a proliferation of monomorphic round cells, organized in nests and focally forming pseudovascular spaces. Immunohistochemical study revealed positivity for epithelial antigen membrane and vimentin. Vascular markers, cytokeratins and S100 protein were negative. A brain CT scan did not show any evidence of intracranial meningioma. The authors describe the case of a cutaneous frontal meningioma in probable relation with previous cranioencephalic trauma.

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          Cutaneous meningiomas--a clinicopathologic study.

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            Meningiomas in 2009: controversies and future challenges.

            Meningiomas are the most common intracranial primary neoplasm in adults. Over recent years, interest in this clinically diverse group of tumors has intensified, bringing new questions and challenges to the fore, particularly in the fields of epidemiology, radiology, pathology, genetics, and treatment. Interest in modern meningioma research has been stimulated by the high tumor prevalence and the advances in technology. The incidence of meningiomas is climbing, and may indicate increased exposure to environmental risk factors or more sensitive diagnostic modalities. Technological advances have dramatically improved radiologic imaging and radiotherapy treatments, and further refinements are under investigation. Furthermore, the current era of tumor genetics and molecular biology is challenging translational researchers to discover new, targeted, therapeutic agents. This review is an update on the recent advances in the understanding of meningiomas and their management, and highlights pertinent research questions to be addressed in the future.
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              Cutaneous meningioma.

              Cutaneous meningioma is a rare tumor that most commonly occurs on the scalp and occurs in both congenital and acquired forms. It invokes a wide clinical differential diagnosis, but diagnosis is based on characteristic histologic and cytologic findings. Congenital lesions can often present years after birth and even in adult patients. Acquired lesions occur in adulthood. We review histologic, cytologic, and electron microscopic findings and explore how these are used to separate this entity from other entities in the differential diagnosis. While ultrastructural and cytologic findings are similar to those of more common intracranial meningiomas, these tumors exhibit a range of histologic differences. A lack of awareness of this entity precludes correct diagnosis.
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                Author and article information

                Journal
                An Bras Dermatol
                An Bras Dermatol
                Anais Brasileiros de Dermatologia
                Sociedade Brasileira de Dermatologia
                0365-0596
                1806-4841
                May-Jun 2015
                May-Jun 2015
                : 90
                : 3 Suppl 1
                : 130-133
                Affiliations
                [1 ]Centro Hospitalar e Universitário de Coimbra (HUC) - Coimbra, Portugal.
                Author notes
                MAILING ADDRESS: Leonor Isabel Castendo Ramos, Praceta Mota Pinto, 3000 Coimbra, Portugal. E-mail: leonoricr@ 123456gmail.com

                Conflict of Interest: None.

                Article
                10.1590/abd1806-4841.20153798
                4540529
                26312695
                9901aba3-9877-4dbd-931d-c2375bfec28f
                © 2015 by Anais Brasileiros de Dermatologia

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 25 June 2014
                : 02 September 2014
                Categories
                Case Report

                histology,immunohistochemistry,meningioma
                histology, immunohistochemistry, meningioma

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