Jordan J. Nostedt:
ORCID: http://orcid.org/0000-0002-3984-5700
Role: InvestigationRole: Writing – original draft
Tom Churchill: Role: InvestigationRole: Writing – review & editing
Sunita Ghosh: Role: Formal analysis
Aducio Thiesen: Role: Investigation
Jessica Hopkins: Role: Investigation
Mackenzie C. Lees: Role: Investigation
Benjamin Adam: Role: Investigation
Darren H. Freed:
ORCID: http://orcid.org/0000-0002-6239-1444
Role: ConceptualizationRole: MethodologyRole: SupervisionRole: Writing – review &
editing
A. M. James Shapiro: Role: SupervisionRole: Writing – review & editing
David L. Bigam: Role: Funding acquisitionRole: MethodologyRole: SupervisionRole: Writing – review
& editing
Akshay Chauhan: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
6
August
2019
Publication date Collection: 2019
Volume: 14
Issue: 8
Electronic Location Identifier: e0220786
Affiliations
[1
]
Department of Surgery, Division of General Surgery, University of Alberta, Edmonton
AB, Canada
[2
]
Department of Surgery, Division of Surgical Research, University of Alberta, Edmonton
AB, Canada
[3
]
Department of Mathematics and Statistical Sciences, University of Alberta, Edmonton
AB, Canada
[4
]
Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton AB,
Canada
[5
]
Department of Physiology, University of Alberta, Edmonton AB, Canada
[6
]
Department of Biomedical Engineering, University of Alberta, Edmonton AB, Canada
[7
]
Department of Surgery, Division of Cardiac Surgery, University of Alberta, Edmonton
AB, Canada
University of Colorado, Anschutz Medical Campus, UNITED STATES
Author notes
Competing Interests: DF is a non-salaried employee of Tevosol, Inc as CSO. Tevosol did not play a role
in study design, data collection and analysis, decision to publish or preparation
of the manuscript. Tevosol did not provide support in any way, whether direct or indirect.
DF’s contributions to the project were under the auspices of his appointment as Associate
Professor in the Department of Surgery, University of Alberta. DF’s commercial affiliation
with Tevosol, Inc does not alter our adherence to PLOS ONE policies on sharing data
and materials.
Author information
Article
Publisher ID:
PONE-D-19-13763
DOI: 10.1371/journal.pone.0220786
PMC ID: 6684160
PubMed ID: 31386697
SO-VID: 992e4b03-6d88-47e1-84a6-ed5751acf860
Copyright © © 2019 Nostedt et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
JN was funded by the University of Alberta Clinician Investigator Program. The funder
provided support in the form of salaries for JN, but did not have any additional role
in the study design, data collection and analysis, decision to publish, or preparation
of the manuscript. The specific roles of this author are articulated in the ‘author
contributions’ section.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Surgical and Invasive Medical Procedures
Subject:
Digestive System Procedures
Subject:
Liver Transplantation
Subject:
Medicine and Health Sciences
Subject:
Surgical and Invasive Medical Procedures
Subject:
Transplantation
Subject:
Organ Transplantation
Subject:
Liver Transplantation
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Blood Vessels
Subject:
Veins
Subject:
Portal Veins
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Blood Vessels
Subject:
Veins
Subject:
Portal Veins
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Epithelial Cells
Subject:
Endothelial Cells
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Epithelium
Subject:
Epithelial Cells
Subject:
Endothelial Cells
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Epithelium
Subject:
Epithelial Cells
Subject:
Endothelial Cells
Subject:
Medicine and Health Sciences
Subject:
Vascular Medicine
Subject:
Ischemia
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Compounds
Subject:
Organic Compounds
Subject:
Amino Acids
Subject:
Basic Amino Acids
Subject:
Histidine
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Organic Chemistry
Subject:
Organic Compounds
Subject:
Amino Acids
Subject:
Basic Amino Acids
Subject:
Histidine
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Amino Acids
Subject:
Basic Amino Acids
Subject:
Histidine
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Liver
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Liver
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Blood Vessels
Subject:
Arteries
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Blood Vessels
Subject:
Arteries
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Body Fluids
Subject:
Bile
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Body Fluids
Subject:
Bile
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Body Fluids
Subject:
Bile
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Body Fluids
Subject:
Bile