Estimating hazard ratios from published Kaplan-Meier survival curves: A methods validation study.

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Abstract

Various statistical methods have been developed to estimate hazard ratios (HRs) from published Kaplan-Meier (KM) curves for the purpose of performing meta-analyses. The objective of this study was to determine the reliability, accuracy, and precision of four commonly used methods by Guyot, Williamson, Parmar, and Hoyle and Henley.

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Journal ID (iso-abbrev): Res Synth Methods

Title: Research synthesis methods

Publisher: Wiley

ISSN (Electronic): 1759-2887

ISSN (Print): 1759-2879

Publication date (Electronic): Sep 2019

Volume: 10

Issue: 3

Affiliations

[1 ] Division of Medical Oncology and Hematology, Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada.

[2 ] Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

[3 ] Canadian Centre for Applied Research in Cancer Control (ARCC), Toronto, Ontario, Canada.

Article

DOI: 10.1002/jrsm.1362

PubMed ID: 31134735

SO-VID: 9b22668b-86cd-421d-96df-8d214e6dc2dc

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Keywords: Kaplan-Meier survival curves,hazard ratios,meta-analysis,validation study

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Keywords: Kaplan-Meier survival curves, hazard ratios, meta-analysis, validation study

Estimating hazard ratios from published Kaplan-Meier survival curves: A methods validation study.

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NeuroImaging Methods

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