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      Fungemia por Trichosporon beigelii: reporte del primer caso en Costa Rica

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          Abstract

          Se reporta el primer caso en Costa Rica, de fungemia por Trichosporon beigelii, en un niño de 7 años, con leucemia mielocítica aguda y que ingresa a la Unidad de Cuidado Intensivo del Hospital Nacional de Niños "Dr. Carlos Sáenz Herrera" con sangrado gastrointestinal y cuadro febril. De los catéteres y de tres hemocultivos se aisla Trichosporon beigelii resistente a Anfotericina B. Tiene evolución rápida y fallece.

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          Tratado de Micología Médica

          WJ Rippon, J. RIPPON, J. W Rippon … (1990)
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            Fungal infections complicating acute leukemia.

            Gerald Bodey (1966)
            Article 0 comments Cited 19 times – based on 0 reviews     Review now
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              Trichosporon beigelii, an emerging pathogen resistant to amphotericin B.

              G. Melcher, Donald Pizzo, G Rinaldi … (1990)
              Trichosporon beigelii caused fatal disseminated infections that were resistant to amphotericin B in two granulocytopenic patients. In vitro susceptibility studies demonstrated that both index strains of T. beigelii were inhibited but not killed by amphotericin B at achievable concentrations in serum. The minimum lethal concentration for both isolates was greater than or equal to 18 micrograms/ml. Five of seven other isolates were found to have a similar pattern of amphotericin B resistance. The fact that the minimum lethal concentration of T. beigelii was many times greater than its MIC was consistent with a resistance pattern of tolerance. We concluded that T. beigelii may be resistant in vitro to amphotericin B and that this in vitro resistance was correlated with refractory, disseminated trichosporonosis in granulocytopenic patients. T. beigelii should be included in the expanding list of amphotericin B-resistant fungi.
              Article 0 comments Cited 17 times – based on 0 reviews     Review now
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                Author and article information

                Contributors
                Marco L Herrera: Role: ND
                Tatiana Moya: Role: ND
                Isabel Duarte: Role: ND
                Allan Bogantes: Role: ND
                Journal
                Journal ID (publisher): rmhnn
                Title: Revista Médica del Hospital Nacional de Niños Dr. Carlos Sáenz Herrera
                Abbreviated Title: Rev. méd. Hosp. Nac. Niños (Costa Rica)
                Publisher: Editorial Nacional de Salud y Seguridad Social (San José )
                ISSN: 1017-8546
                Publication date (Print): 1995
                Volume: 30
                Issue: 1-2
                Pages: 27-30
                Affiliations
                [1 ] Hospital Nacional de Niños Dr. Carlos Sáenz Herrera Costa Rica
                Article
                Publisher ID: S1017-85461995000100004
                SO-VID: 9f040de5-1157-4c87-8070-5cf4313e6f62
                License:

                http://creativecommons.org/licenses/by/4.0/

                History
                Product

                SciELO Costa Rica

                Self URI (journal page): http://www.scielo.sa.cr/scielo.php?script=sci_serial&pid=1017-8546&lng=en

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