Relationship between addictions and obesity, physical activity and vascular aging in young adults (EVA-Adic study): a research protocol of a cross-sectional study

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Abstract

Background

Behavioral and substance addictions are prevalent health problems that, alongside obesity, are linked to reduced physical activity and increased sedentary time. Similarly, arterial stiffness and vascular aging are processes that begin gradually at an early age and are closely associated with morbidity and mortality from cardiovascular diseases. The main objective of this study is to analyze how addictions are related to obesity and body fat distribution, physical activity, sedentary time, arterial stiffness and vascular aging, as well as sleep quality, cognitive function and gender differences in young adults aged between 18 and 34 years.

Methods

This cross-sectional descriptive observational study will analyze data from 500 subjects (250 men and 250 women) aged 18–34 without cardiovascular disease, selected by simple random sampling with replacement from the urban population of the city center of Salamanca (34,044 people aged 18–34, with 18,450 women and 15,594 men). Behavioral and substance addictions, as well as sleep quality and cognitive impairment will be assessed using questionnaires. The Pittisburg Sleep Quality Index (PSQI) will be used to measure sleep quality and the Ford questionnaire will be used to measure insomnia in response to stress. For obesity, weight, height, waist and hip circumference, body composition will be measured with the Inbody 230 ^® impedance meter. For physical activity and sedentary time, we will use the Actigraph ^® accelerometer alongside the international physical activity questionnaire (IPAQ) and the Marshall questionnaire. The Sphygmocor System ^® will be used for pulse wave analysis and carotid-femoral pulse wave velocity (cfPWV), while the Vasera VS-2000 ^® will measure cardio ankle vascular index (CAVI) and brachial-ankle pulse wave velocity (baPWV). Vascular aging will be calculated with the 10th and 90th percentiles of cfPWV or baPWV. Demographic, analytical variables will be collected, as will data to assess vascular, cardiac, renal, and brain injury.

Discussion

Addictions are on the rise in today’s society, affecting the mental health and well-being of those who suffer from them, generating important social problems such as job loss, family dysfunction, debt and social isolation. Together with obesity, they are prevalent health problems in young adults and are associated with lower physical activity and higher sedentary time. Meanwhile, arterial stiffness and vascular aging are processes that begin gradually at an early age and determine morbidity and mortality caused by cardiovascular diseases. The results of this project will allow us to understand the situation regarding behavioral and substance addictions in young adults. Better understanding of these addictions will in turn facilitate the development of more effective prevention strategies and intervention programs, which can then reduce the negative impact at both the individual and societal levels.

Clinical trial registration

[ ClinicalTrials.gov], identifier [NCT05819840].

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Most cited references 91

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Author and article information

Contributors

Sara Vicente-Gabriel: Role:

Cristina Lugones-Sánchez: Role:

Olaya Tamayo-Morales: URI : https://loop.frontiersin.org/people/2323219/overviewRole:

Alberto Vicente Prieto: Role:

Susana González-Sánchez: URI : https://loop.frontiersin.org/people/2402378/overviewRole:

Sandra Conde Martín: Role:

Marta Gómez-Sánchez: Role:

Emiliano Rodríguez-Sánchez: URI : https://loop.frontiersin.org/people/2276129/overviewRole:

Luis García-Ortiz: URI : https://loop.frontiersin.org/people/2198800/overviewRole:

Leticia Gómez-Sánchez: Role: Role:

Manuel A. Gómez-Marcos: URI : https://loop.frontiersin.org/people/2404542/overviewRole: Role:

Journal

Journal ID (nlm-ta): Front Public Health

Journal ID (iso-abbrev): Front Public Health

Journal ID (publisher-id): Front. Public Health

Title: Frontiers in Public Health

Publisher: Frontiers Media S.A.

ISSN (Electronic): 2296-2565

Publication date (Electronic): 26 January 2024

Publication date Collection: 2024

Volume: 12

Electronic Location Identifier: 1322437

Affiliations

[1] ¹Primary Care Research Unit of Salamanca (APISAL), Salamanca Primary Care Management, Institute of Biomedical Research of Salamanca (IBSAL) , Salamanca, Spain

[2] ²Intensive Care Unit, Salamanca University Hospital , Salamanca, Spain

[3] ³Research Network on Chronicity, Primary Care and Health Promotion (RICAPPS) , Barcelona, Spain

[4] ⁴Salamanca Primary Care Management, Castilla and León Health Service–SACYL , Salamanca, Spain

[5] ⁵Home Hospitalization Unit, Marqués de Valdecilla University Hospital , Santander, Spain

[6] ⁶Department of Medicine, University of Salamanca , Salamanca, Spain

[7] ⁷Department of Biomedical and Diagnostic Sciences, University of Salamanca , Salamanca, Spain

[8] ⁸Emergency Department, La Paz University Hospital , Madrid, Spain

Author notes

Edited by: M. Barton Laws, Brown University, United States

Reviewed by: Eduardo Gutiérrez-Abejón, Universidad de Valladolid, Spain; Brian Reed, Molloy College, United States

*Correspondence: Olaya Tamayo-Morales, olayatm@ 123456usal.es

^†These authors have contributed equally to this work and share first authorship

^‡These authors have contributed equally to this work and share senior authorship

Article

DOI: 10.3389/fpubh.2024.1322437

PMC ID: 10853417

PubMed ID: 38344236

SO-VID: 9fb4d298-fd13-4c6c-91a0-cf428d8df1c3

Copyright © Copyright © 2024 Vicente-Gabriel, Lugones-Sánchez, Tamayo-Morales, Vicente Prieto, González-Sánchez, Conde Martín, Gómez-Sánchez, Rodríguez-Sánchez, García-Ortiz, Gómez-Sánchez, Gómez-Marcos and EVA-Adic Investigators Group.

License:

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

History

Date received : 16 October 2023

Date accepted : 08 January 2024

Page count

Figures: 1, Tables: 2, Equations: 0, References: 91, Pages: 12, Words: 9948

Funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study has been funded by the Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III (ISCIII) (RD21/0016/0010), Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS) was funded by the European Union-Next Generation EU, Facility for Recovery and Resilience (MRR). Government of Castilla y León (GRS 2500/B/22) and the Institute for Biomedical Research of Salamanca (IBSAL) (IBYE22/00003) also collaborated with the funding of this study through the research projects. The funding entities had no role in the study design, data analysis, reporting of results, or the decision to submit the manuscript for publication.

Custom metadata

section-at-acceptance Substance Use Disorders and Behavioral Addictions

Keywords: substance-related disorders,gambling,internet use,technology addiction,obesity,healthy lifestyle,physical activity,vascular stiffness

Data availability:

Keywords: substance-related disorders, gambling, internet use, technology addiction, obesity, healthy lifestyle, physical activity, vascular stiffness

Relationship between addictions and obesity, physical activity and vascular aging in young adults (EVA-Adic study): a research protocol of a cross-sectional study

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Abstract

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Discussion

Clinical trial registration

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UCL: UN SDG 03 Good Health and Well-Being

Most cited references 91

Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects.

The REDCap consortium: Building an international community of software platform partners

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