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      Options in the management of tuberculous ureteric stricture

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          Abstract

          Ureteric stricture is a feared manifestation of genitourinary tuberculosis (TB) with the commonest site being the lower ureter. The purpose of this review is to discuss the management options for this condition. Literature search was done using PubMed and all articles on TB and ureteric stricture were reviewed published between 1990 till September 2007. The exact site and length of stricture must be defined with radioimaging (intravenous urography, retrograde, or antegrade pyelography) and renal function be quantified. The treatment of stricture mostly requires some kind of intervention after a brief period of antituberculous medicines with or without steroids. For uncomplicated/simple strictures (short segment, passable, with renal function >25%, good bladder capacity) endourologic option should be used which usually means double-J stenting with or without balloon dilatation. For complicated/complex strictures (long segment, dense fibrosis, with renal function <20%, small bladder capacity) regular surgical options should be considered which usually means ureteroureterostomy or ureteropyelostomy for upper ureteric strictures, intubated ureterostomy, or transureteroureterostomy for midureteric strictures, psoas hitch/Boari flap for lower ureteric strictures or ileal ureter/autotransplantation for whole length/multiple strictures.

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          Most cited references39

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          Buccal mucosal grafts in the treatment of ureteric lesions.

          H Naudé (1999)
          To devise a procedure capable of curing complicated ureteric strictures and replacing segments of lost ureter, without the long-term infective complications of bowel interposition or the surgical magnitude of autotransplantation. Four patients with complicated strictures and one with segmental ureteric loss were treated by buccal mucosal patch grafts and an omental wrap. One patient with segmental ureteric loss was treated by interposition of a tubularized buccal mucosal graft. Ureteric patency was established and maintained in all patients, there were no complications and urine was sterile in all patients at follow-up. In a few patients, buccal mucosal patch graft repair has proved capable of maintaining patency and good urinary drainage in patients with complicated ureteric strictures. Segmental ureteric loss has been replaced in one patient by a patch graft and in another by tubularized graft interposition.
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            Long-term results of endoureterotomy for benign ureteral and ureteroenteric strictures.

            We reviewed the results of endoureterotomy for benign ureteral and ureteroenteric strictures to determine efficacy and factors associated with a successful outcome. Followup was available for 69 patients undergoing 77 endoureterotomies. Success was defined as symptomatic improvement and radiographic resolution of obstruction. Kaplan-Meier survival curves were constructed and data were analyzed with a Cox proportional hazards model. None of 9 procedures in patients with the ipsilateral kidney contributing less than 25% of total renal function was successful. Among the 38 remaining benign ureteral stricture treatments with ipsilateral function 25% or greater with a median followup of 28.4 months among successful cases the 3-year success rate was 80%. No procedure failed beyond 11 months and there were 25 patients at risk beyond this point. Among the 30 remaining ureteroenteric stricture treatments with ipsilateral function 25% or greater the success rates at 1, 2 and 3 years were 73, 51 and 32%, respectively. Failures were noted during the first 36 months but none occurred later and 5 patients were at risk beyond this point. Overall, complete or tight strictures were less successfully treated. A nonischemic etiology, a stent 12F or greater and injection of triamcinolone into the bed of the incised stricture were associated with better outcome for strictures longer than 1 cm. Endoureterotomy of benign ureteral strictures is associated with an excellent outcome (80% success at 3 years). Endoscopic treatment of ureteroenteric strictures is less successful but still offers a reasonable first step (32% 3-year success rate). For all strictures failure is likely if ipsilateral renal function is poor. For strictures longer than 1 cm. use of a stent 12F or greater and injection of triamcinolone appear to be beneficial.
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              High ureteral injuries. Management by autotransplantation of the kidney.

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                Author and article information

                Journal
                Indian J Urol
                IJU
                Indian Journal of Urology : IJU : Journal of the Urological Society of India
                Medknow Publications (India )
                0970-1591
                1998-3824
                Jul-Sep 2008
                : 24
                : 3
                : 376-381
                Affiliations
                Department of Urology, CSM Medical University, Lucknow, UP, India
                Author notes
                For correspondence: Dr. Apul Goel, Department of Urology, CSM Medical University, Lucknow, UP, India. E-mail: goelapul1@ 123456rediffmail.com
                Article
                IJU-24-376
                10.4103/0970-1591.42621
                2684368
                19468472
                a01073b8-d9d0-4e66-b23d-de1261d0dd6b
                © Indian Journal of Urology

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Categories
                Symposium

                Urology
                tuberculosis,ureter,ureteric stricture
                Urology
                tuberculosis, ureter, ureteric stricture

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