TGF-β1 induces epithelial-to-mesenchymal transition in chronic rhinosinusitis with nasal polyps through microRNA-182.

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Abstract

Epithelial-to-mesenchymal transition (EMT) in nasal epithelial cells is involved in tissue remodeling of chronic rhinosinusitis with nasal polyps (CRSwNP). Our study investigated the molecular mechanisms that microRNA-182 (miR-182) regulated EMT in eosinophilic (Eos) and non-eosinophilic (non-Eos) CRSwNP.

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Journal

Journal ID (iso-abbrev): Asian Pac J Allergy Immunol

Title: Asian Pacific journal of allergy and immunology

Publisher: Allergy, Asthma, and Immunology Association of Thailand

ISSN: 0125-877X

ISSN (Print): 0125-877X

Publication date (Electronic): Dec 26 2021

Affiliations

[1 ] Allergy Center, Department of Otolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.

[2 ] The Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine, University of Chinese Academy of Sciences, Shanghai, China.

Article

DOI: 10.12932/AP-040921-1224

PubMed ID: 34953475

SO-VID: a10ece46-8e67-4e2b-a212-4e4e95cac6a7

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