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      Uptake of COVID-19 vaccines and associated factors among adults in Uganda: a cross-sectional survey

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          Abstract

          Objective

          COVID-19 pandemic remains one of the most significant public health challenges ever faced globally. Vaccines are key to ending the pandemic as well as minimise its consequences. This study determined the uptake of COVID-19 vaccines and associated factors among adults in Uganda.

          Design, setting and participants

          We conducted a cross-sectional mobile phone survey among adults in Uganda.

          Main outcome variable

          Participants reported their uptake of COVID-19 vaccines.

          Results

          Of the participants contacted, 94% (1173) completed the survey. Overall, 49.7% had received COVID-19 vaccines with 19.2% having obtained a full dose and 30.5% an incomplete dose. Among the unvaccinated, 91.0% indicated intention to vaccinate. Major reasons for vaccine uptake were protection of self from COVID-19 (86.8%) and a high perceived risk of getting the virus (19.6%). On the other hand, non-uptake was related to vaccine unavailability (42.4%), lack of time (24.1%) and perceived safety (12.5%) and effectiveness concerns (6.9%). The factors associated with receiving COVID-19 vaccines were older age (≥65 years) (Adjusted Prevalence Ratio (APR)=1.32 (95% CI: 1.08 to 1.61)), secondary (APR=1.36 (95% CI: 1.12 to 1.65)) or tertiary education (APR=1.62 (95% CI: 1.31 to 2.00)) and health workers as a source of information on COVID-19 (APR=1.26 (95% CI: 1.10 to 1.45)). Also, reporting a medium-income (APR=1.24 (95% CI: 1.02 to 1.52)) and residence in Northern (APR=1.55, 95% CI: 1.18 to 2.02) and Central regions (APR=1.48, 95% CI: 1.16 to 1.89) were associated with vaccine uptake.

          Conclusions

          Uptake of COVID-19 vaccines was moderate in this sample and was associated with older age, secondary and tertiary education, medium-income, region of residence and health workers as a source of COVID-19 information. Efforts are needed to increase access to vaccines and should use health workers as champions to enhance uptake.

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          Most cited references25

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          Vaccine hesitancy: Definition, scope and determinants.

          The SAGE Working Group on Vaccine Hesitancy concluded that vaccine hesitancy refers to delay in acceptance or refusal of vaccination despite availability of vaccination services. Vaccine hesitancy is complex and context specific, varying across time, place and vaccines. It is influenced by factors such as complacency, convenience and confidence. The Working Group retained the term 'vaccine' rather than 'vaccination' hesitancy, although the latter more correctly implies the broader range of immunization concerns, as vaccine hesitancy is the more commonly used term. While high levels of hesitancy lead to low vaccine demand, low levels of hesitancy do not necessarily mean high vaccine demand. The Vaccine Hesitancy Determinants Matrix displays the factors influencing the behavioral decision to accept, delay or reject some or all vaccines under three categories: contextual, individual and group, and vaccine/vaccination-specific influences.
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            COVID-19 pandemic and mental health consequences: systematic review of the current evidence

            Highlights • COVID-19 patients displayed high levels of PTSS and increased levels of depression. • Patients with preexisting psychiatric disorders reported worsening of psychiatric symptoms. • Higher levels of psychiatric symptoms were found among health care workers. • A decrease in psychological well-being was observed in the general public. • However, well conducted large-scale studies are highly needed.
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              Vaccine hesitancy: an overview.

              Despite being recognized as one of the most successful public health measures, vaccination is perceived as unsafe and unnecessary by a growing number of individuals. Lack of confidence in vaccines is now considered a threat to the success of vaccination programs. Vaccine hesitancy is believed to be responsible for decreasing vaccine coverage and an increasing risk of vaccine-preventable disease outbreaks and epidemics. This review provides an overview of the phenomenon of vaccine hesitancy. First, we will characterize vaccine hesitancy and suggest the possible causes of the apparent increase in vaccine hesitancy in the developed world. Then we will look at determinants of individual decision-making about vaccination.
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                Author and article information

                Journal
                BMJ Open
                BMJ Open
                bmjopen
                bmjopen
                BMJ Open
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                2044-6055
                2023
                17 March 2023
                17 March 2023
                : 13
                : 3
                : e067377
                Affiliations
                [1 ]departmentDepartment of Disease Control and Environmental Health, School of Public Health, College of Health Sciences , Makerere University , Kampala, Uganda
                [2 ]departmentDepartment of Political Science , Massachusetts Institute of Technology , Cambridge, Massachusetts, USA
                [3 ]departmentDepartment of Community Health and Behavioral Sciences, School of Public Health, College of Health Sciences , Makerere University , Kampala, Uganda
                [4 ]departmentDepartment of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences , Makerere University , Kampala, Uganda
                [5 ]departmentDepartment of Health Policy, Planning and Management, School of Public Health, College of Health Sciences , Makerere University , Kampala, Uganda
                [6 ]Bill & Melinda Gates Foundation , Seattle, Washington, USA
                Author notes
                [Correspondence to ] Rawlance Ndejjo; rndejjo@ 123456musph.ac.ug
                Author information
                http://orcid.org/0000-0001-9263-557X
                http://orcid.org/0000-0003-0700-3784
                http://orcid.org/0000-0002-0354-9571
                http://orcid.org/0000-0002-6405-015X
                http://orcid.org/0000-0002-5264-4655
                Article
                bmjopen-2022-067377
                10.1136/bmjopen-2022-067377
                10030279
                36931667
                a14ec5e2-e3ec-4f41-83b6-141a29115788
                © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See:  https://creativecommons.org/licenses/by/4.0/.

                History
                : 10 August 2022
                : 27 February 2023
                Funding
                Funded by: Bill & Melinda Gates Foundation;
                Award ID: INV-019313
                Categories
                Public Health
                1506
                2474
                1724
                Original research
                Custom metadata
                unlocked
                free

                Medicine
                covid-19,public health,infectious diseases
                Medicine
                covid-19, public health, infectious diseases

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