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Role of PI3K/Akt signaling in the protective effect of magnesium sulfate against ischemia-perfusion injury of small intestine in rats.
Shi-da Chen
1 ,
Ya-bin Chen ,
You Peng ,
Jia Xu ,
Su-shan Chen ,
Jun-long Zhang ,
Zheng-zhang Li ,
Zhi Tan
Jun 2010
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Abstract
The protective effects of magnesium sulfate against ischemia-reperfusion injury of the small intestine in Sprague-Dawley (SD) rats have been confirmed in our previous research. However, its exact mechanism is unclear. This study was to evaluate the role of PI3K/Akt signal pathway in the protective effect of magnesium sulfate against ischemia-reperfusion injury of the small intestine in SD rats.