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      Sofosbuvir and Ledipasvir for 8 Weeks for the Treatment of Chronic Hepatitis C Virus (HCV) Infection in HCV-Monoinfected and HIV-HCV-Coinfected Individuals: Results From the German Hepatitis C Cohort (GECCO-01).

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          Abstract

          Shortening the duration of treatment with HCV direct-acting antivirals (DAAs) leads to substantial cost reductions. According to the label, sofosbuvir and ledipasvir can be prescribed for 8 weeks (SL8) in noncirrhotic women or men with HCV genotype 1 and low viral loads. However, real-world data about the efficacy and safety of SL8 are largely missing.

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          Author and article information

          Journal
          Clin. Infect. Dis.
          Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
          Oxford University Press (OUP)
          1537-6591
          1058-4838
          November 15 2016
          : 63
          : 10
          Affiliations
          [1 ] Center for Infectiology Berlin.
          [2 ] Center for Interdisciplinary Medicine Muenster.
          [3 ] Faculty of Medicine, Department of Surgery and Cancer, Imperial College London, United Kingdom.
          [4 ] Gastroenterology Practice, Herne.
          [5 ] Infektiologikum, Frankfurt.
          [6 ] Infectiology Center in Hamburg.
          [7 ] Center for HIV and Hepatogastroenterology, Duesseldorf.
          [8 ] Ambulanzzentrum Virushepatologie, University Medical Center Hamburg-Eppendorf and DZIF Partner Site, Hamburg.
          [9 ] Medical Department I, University Hospital, Bonn.
          [10 ] Klinische Arbeitsgemeinschaft AIDS, Bonn.
          [11 ] Gastroenterology Practice, Leverkusen, Germany.
          Article
          ciw567
          10.1093/cid/ciw567
          27535952
          a2aca82b-d274-470c-8604-2ad6d872035f
          History

          sofosbuvir,8 weeks,HIV coinfection,ledipasvir,short course treatment

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