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      Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy

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          Abstract

          <p class="first" id="d5823554e245">Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium-glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. </p>

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          Author and article information

          Journal
          Title: New England Journal of Medicine
          Abbreviated Title: N Engl J Med
          Publisher: Massachusetts Medical Society
          ISSN (Print): 0028-4793
          ISSN (Electronic): 1533-4406
          Publication date Created: April 14 2019
          Publication date (Electronic): April 14 2019
          Affiliations
          [1 ]From the George Institute for Global Health, University of New South Wales Sydney (V.P., M.J.J., B.N., S. Bompoint), the Royal North Shore Hospital (V.P.), Concord Repatriation General Hospital (M.J.J.), and the Charles Perkins Centre, University of Sydney (B.N.), Sydney, and the Kolling Institute of Medical Research, Sydney Medical School, University of Sydney, Royal North Shore Hospital, St. Leonards, NSW (C.P.) — all in Australia; Imperial College London (B.N.) and the Department of Renal Medicine,...
          Article
          DOI: 10.1056/NEJMoa1811744
          PubMed ID: 30990260
          SO-VID: a3584a12-c083-448c-b9d6-084ee4c78947
          Copyright © © 2019
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