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Diastolic hypotension is an unrecognized risk factor for β-agonist-associated myocardial injury in children with asthma.
Syana M Sarnaik
1 ,
Richard A Saladino ,
Mioara Manole ,
Raymond A Pitetti ,
Gaurav Arora ,
Bradley A Kuch ,
Richard A Orr ,
Kathryn A Felmet
Jul 2013
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Abstract
Tachycardia and diastolic hypotension have been associated with β-2 agonist use. In the setting of β-agonist-induced chronotropy and inotropy, diastolic hypotension may limit myocardial blood flow. We hypothesized that diastolic hypotension is associated with β-agonist use and that diastolic hypotension and tachycardia are associated with biochemical evidence of myocardial injury in children with asthma.