To assess the pain intensity of two intracameral anesthetic solutions in patients undergoing cataract surgery and evaluate the factors influencing the patients’ postoperative activities.
Sixty-two patients undergoing cataract surgery were randomized to receive the study drug – a manufactured solution of 0.02% tropicamide/0.31% phenylephrine/1% lidocaine (Mydrane) or a traditional anesthetic formulation - solution of 1% lidocaine/0.025% adrenaline as an intraocular anesthetic. The pain intensity was assessed by Visual Analog Scale for Pain (VAS Pain) and Brief Pain Inventory-short form (BPI) on the next day after the surgery.
The mean pain score measured preoperatively with VAS Pain was 0.34 in Mydrane group and 0.09 in the reference group ( p = 0.51). There were no statistically significant differences between the two anesthetic methods with respect to pain intensity during the surgery ( p = 0.94) and the influence of pain during the last 24 h on activity ( p = 0.79), mood ( p = 0.31), social contacts ( p = 0.29), sleep ( p = 0.5) and the joy of life ( p = 0.39). Additionally, there was no statistically significant influence of age, sex, lateralization, co-existing ophthalmological diseases ( p = 0.98) and post-operative complications ( p = 0.4) on the experienced pain measured during the surgery and in the last 24 h.