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      A network analysis of anxiety and depression symptoms among Chinese nurses in the late stage of the COVID-19 pandemic

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          Abstract

          Background

          Nurses are at high risk for depression and anxiety symptoms after the outbreak of the COVID-19 pandemic. We aimed to assess the network structure of anxiety and depression symptoms among Chinese nurses in the late stage of this pandemic.

          Method

          A total of 6,183 nurses were recruited across China from Oct 2020 to Apr 2021 through snowball sampling. We used Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder scale-7 (GAD-7) to assess depression and anxiety, respectively. We used the Ising model to estimate the network. The index “expected influence” and “bridge expected influence” were applied to determine the central symptoms and bridge symptoms of the anxiety-depression network. We tested the stability and accuracy of the network via the case-dropping procedure and non-parametric bootstrapping procedure.

          Result

          The network had excellent stability and accuracy. Central symptoms included “restlessness”, “trouble relaxing”, “sad mood”, and “uncontrollable worry”. “Restlessness”, “nervous”, and “suicidal thoughts” served as bridge symptoms.

          Conclusion

          Restlessness emerged as the strongest central and bridge symptom in the anxiety-depression network of nurses. Intervention on depression and anxiety symptoms in nurses should prioritize this symptom.

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          Most cited references44

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          Estimating psychological networks and their accuracy: A tutorial paper

          The usage of psychological networks that conceptualize behavior as a complex interplay of psychological and other components has gained increasing popularity in various research fields. While prior publications have tackled the topics of estimating and interpreting such networks, little work has been conducted to check how accurate (i.e., prone to sampling variation) networks are estimated, and how stable (i.e., interpretation remains similar with less observations) inferences from the network structure (such as centrality indices) are. In this tutorial paper, we aim to introduce the reader to this field and tackle the problem of accuracy under sampling variation. We first introduce the current state-of-the-art of network estimation. Second, we provide a rationale why researchers should investigate the accuracy of psychological networks. Third, we describe how bootstrap routines can be used to (A) assess the accuracy of estimated network connections, (B) investigate the stability of centrality indices, and (C) test whether network connections and centrality estimates for different variables differ from each other. We introduce two novel statistical methods: for (B) the correlation stability coefficient, and for (C) the bootstrapped difference test for edge-weights and centrality indices. We conducted and present simulation studies to assess the performance of both methods. Finally, we developed the free R-package bootnet that allows for estimating psychological networks in a generalized framework in addition to the proposed bootstrap methods. We showcase bootnet in a tutorial, accompanied by R syntax, in which we analyze a dataset of 359 women with posttraumatic stress disorder available online. Electronic supplementary material The online version of this article (doi:10.3758/s13428-017-0862-1) contains supplementary material, which is available to authorized users.
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            Mental Health and Psychosocial Problems of Medical Health Workers during the COVID-19 Epidemic in China

            Objective We explored whether medical health workers had more psychosocial problems than nonmedical health workers during the COVID-19 outbreak. Methods An online survey was run from February 19 to March 6, 2020; a total of 2,182 Chinese subjects participated. Mental health variables were assessed via the Insomnia Severity Index (ISI), the Symptom Check List-revised (SCL-90-R), and the Patient Health Questionnaire-4 (PHQ-4), which included a 2-item anxiety scale and a 2-item depression scale (PHQ-2). Results Compared with nonmedical health workers (n = 1,255), medical health workers (n = 927) had a higher prevalence of insomnia (38.4 vs. 30.5%, p < 0.01), anxiety (13.0 vs. 8.5%, p < 0.01), depression (12.2 vs. 9.5%; p< 0.04), somatization (1.6 vs. 0.4%; p < 0.01), and obsessive-compulsive symptoms (5.3 vs. 2.2%; p < 0.01). They also had higher total scores of ISI, GAD-2, PHQ-2, and SCL-90-R obsessive-compulsive symptoms (p ≤ 0.01). Among medical health workers, having organic disease was an independent factor for insomnia, anxiety, depression, somatization, and obsessive-compulsive symptoms (p < 0.05 or 0.01). Living in rural areas, being female, and being at risk of contact with COVID-19 patients were the most common risk factors for insomnia, anxiety, obsessive-compulsive symptoms, and depression (p < 0.01 or 0.05). Among nonmedical health workers, having organic disease was a risk factor for insomnia, depression, and obsessive-compulsive symptoms (p < 0.01 or 0.05). Conclusions During the COVID-19 outbreak, medical health workers had psychosocial problems and risk factors for developing them. They were in need of attention and recovery programs.
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              Network analysis: an integrative approach to the structure of psychopathology.

              In network approaches to psychopathology, disorders result from the causal interplay between symptoms (e.g., worry → insomnia → fatigue), possibly involving feedback loops (e.g., a person may engage in substance abuse to forget the problems that arose due to substance abuse). The present review examines methodologies suited to identify such symptom networks and discusses network analysis techniques that may be used to extract clinically and scientifically useful information from such networks (e.g., which symptom is most central in a person's network). The authors also show how network analysis techniques may be used to construct simulation models that mimic symptom dynamics. Network approaches naturally explain the limited success of traditional research strategies, which are typically based on the idea that symptoms are manifestations of some common underlying factor, while offering promising methodological alternatives. In addition, these techniques may offer possibilities to guide and evaluate therapeutic interventions.
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                Author and article information

                Contributors
                Journal
                Front Public Health
                Front Public Health
                Front. Public Health
                Frontiers in Public Health
                Frontiers Media S.A.
                2296-2565
                02 November 2022
                2022
                02 November 2022
                : 10
                : 996386
                Affiliations
                [1] 1Department of Psychiatry and National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University , Changsha, China
                [2] 2Clinical Nursing Teaching and Research Section, The Second Xiangya Hospital, Central South University , Changsha, China
                [3] 3Department of Psychology, College of Education, Hunan First Normol University , Changsha, China
                [4] 4Department of Psychiatry, Hunan Brain Hospital (Hunan Second People's Hospital , Changsha, China
                [5] 5Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine , Shanghai, China
                [6] 6Department of Psychiatry, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College , Hangzhou, China
                [7] 7College of Health Solutions, Arizona State University , Phoenix, AZ, United States
                [8] 8Department of Psychiatry, Sir Run Shaw Hospital, School of Medicine, Zhejiang University , Hangzhou, China
                Author notes

                Edited by: Lawrence T. Lam, University of Technology Sydney, Australia

                Reviewed by: Elsa Vitale, Bari Local Health Authority, Italy; Pinar Guzel Ozdemir, Yüzüncü Yil University, Turkey

                *Correspondence: Tieqiao Liu liutieqiao123@ 123456csu.edu.cn

                This article was submitted to Public Mental Health, a section of the journal Frontiers in Public Health

                †These authors have contributed equally to this work and share first authorship

                Article
                10.3389/fpubh.2022.996386
                9667894
                36408014
                aa016a08-13e5-4733-b02f-281a4b035868
                Copyright © 2022 Peng, Chen, Liang, Liu, Chen, Wang, Yang, Wang, Li, Wang, Hao, He, Wang, Zhang, Ma, He, Zhou, Li, Xu, Long, Qi, Tang, Liao, Tang, Wu and Liu.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 17 July 2022
                : 10 October 2022
                Page count
                Figures: 5, Tables: 2, Equations: 0, References: 44, Pages: 10, Words: 5310
                Funding
                Funded by: Natural Science Foundation of Hunan Province, doi 10.13039/501100004735;
                Categories
                Public Health
                Original Research

                depression,anxiety,network analysis,covid-19 pandemic,nurse
                depression, anxiety, network analysis, covid-19 pandemic, nurse

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