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      Intelligent Algorithm-Based Multislice Spiral Computed Tomography to Diagnose Coronary Heart Disease

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      Computational and Mathematical Methods in Medicine
      Hindawi

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          Abstract

          In this study, dictionary learning and expectation maximization reconstruction (DLEM) was combined to denoise 64-slice spiral CT images, and results of coronary angiography (CAG) were used as standard to evaluate its clinical value in diagnosing coronary artery diseases. 120 patients with coronary heart disease (CHD) confirmed by CAG examination were retrospectively selected as the research subjects. According to the random number table method, the patients were divided into two groups: the control group was diagnosed by conventional 64-slice spiral CT images, and the observation group was diagnosed by 64-slice spiral CT images based on the DLEM algorithm, with 60 cases in both groups. With CAG examination results as the standard, the diagnostic effects of the two CT examination methods were compared. The results showed that when the number of iterations of maximum likelihood expectation maximization (MLEM) algorithm reached 50, the root mean square error (RMSE) and peak signal to noise ratio (PSNR) values were similar to the results obtained by the DLEM algorithm under a number of iterations of 10 when the RMSE and PSNR values were 18.9121 dB and 74.9911 dB, respectively. In the observation group, 28.33% (17/60) images were of grade 4 or above before processing; after processing, it was 70% (42/60), significantly higher than the proportion of high image quality before processing. The overall diagnostic consistency, sensitivity, specificity, and accuracy (88.33%, 86.67%, 80%, and 85%) of the observation group were better than those in the control group (60.46%, 62.5%, 58.33%, and 61.66%). In conclusion, the DLEM algorithm has good denoising effect on 64-slice spiral CT images, which significantly improves the accuracy in the diagnosis of coronary artery stenosis and has good clinical diagnostic value and is worth promoting.

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          Depression and coronary heart disease

          Depression is a highly prevalent risk factor for incident coronary heart disease (CHD) and for cardiovascular morbidity and mortality in patients with established CHD. In this Review, Carney and Freedland consider the evidence for depression as a cardiac risk factor, and summarize the biological and behavioural mechanisms that might link depression to CHD. They also consider whether treatment of depression can prevent cardiac morbidity and mortality in patients with CHD.
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            Genetics and Genomics of Congenital Heart Disease.

            Congenital heart disease is the most common birth defect, and because of major advances in medical and surgical management, there are now more adults living with congenital heart disease (CHD) than children. Until recently, the cause of the majority of CHD was unknown. Advances in genomic technologies have discovered the genetic causes of a significant fraction of CHD, while at the same time pointing to remarkable complexity in CHD genetics. This review will focus on the evidence for genetic causes underlying CHD and discuss data supporting both monogenic and complex genetic mechanisms underlying CHD. The discoveries from CHD genetic studies draw attention to biological pathways that simultaneously open the door to a better understanding of cardiac development and affect clinical care of patients with CHD. Finally, we address clinical genetic evaluation of patients and families affected by CHD.
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              Semi-Supervised Support Vector Machine for Digital Twins Based Brain Image Fusion

              The purpose is to explore the feature recognition, diagnosis, and forecasting performances of Semi-Supervised Support Vector Machines (S3VMs) for brain image fusion Digital Twins (DTs). Both unlabeled and labeled data are used regarding many unlabeled data in brain images, and semi supervised support vector machine (SVM) is proposed. Meantime, the AlexNet model is improved, and the brain images in real space are mapped to virtual space by using digital twins. Moreover, a diagnosis and prediction model of brain image fusion digital twins based on semi supervised SVM and improved AlexNet is constructed. Magnetic Resonance Imaging (MRI) data from the Brain Tumor Department of a Hospital are collected to test the performance of the constructed model through simulation experiments. Some state-of-art models are included for performance comparison: Long Short-Term Memory (LSTM), Convolutional Neural Network (CNN), Recurrent Neural Network (RNN), AlexNet, and Multi-Layer Perceptron (MLP). Results demonstrate that the proposed model can provide a feature recognition and extraction accuracy of 92.52%, at least an improvement of 2.76% compared to other models. Its training lasts for about 100 s, and the test takes about 0.68 s. The Root Mean Square Error (RMSE) and Mean Absolute Error (MAE) of the proposed model are 4.91 and 5.59%, respectively. Regarding the assessment indicators of brain image segmentation and fusion, the proposed model can provide a 79.55% Jaccard coefficient, a 90.43% Positive Predictive Value (PPV), a 73.09% Sensitivity, and a 75.58% Dice Similarity Coefficient (DSC), remarkably better than other models. Acceleration efficiency analysis suggests that the improved AlexNet model is suitable for processing massive brain image data with a higher speedup indicator. To sum up, the constructed model can provide high accuracy, good acceleration efficiency, and excellent segmentation and recognition performances while ensuring low errors, which can provide an experimental basis for brain image feature recognition and digital diagnosis.
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                Author and article information

                Contributors
                Journal
                Comput Math Methods Med
                Comput Math Methods Med
                cmmm
                Computational and Mathematical Methods in Medicine
                Hindawi
                1748-670X
                1748-6718
                2022
                13 January 2022
                : 2022
                : 4900803
                Affiliations
                Department of Cardiovascular Medicine, The Third Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China
                Author notes

                Academic Editor: Osamah Ibrahim Khalaf

                Author information
                https://orcid.org/0000-0002-3647-5206
                https://orcid.org/0000-0002-9684-9978
                Article
                10.1155/2022/4900803
                8776441
                35069783
                abf0bf30-aeaf-4164-9896-ee4a6ae34aeb
                Copyright © 2022 Shaowen Tan and Zili Xu.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 24 October 2021
                : 11 December 2021
                : 22 December 2021
                Categories
                Research Article

                Applied mathematics
                Applied mathematics

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