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      Human Health Risk Assessment Based on Toxicity Characteristic Leaching Procedure and Simple Bioaccessibility Extraction Test of Toxic Metals in Urban Street Dust of Tianjin, China

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          Abstract

          The potential ecological and human health risk related with urban street dust from urban areas of Tianjin, China was quantitatively analyzed using the method of toxicity characteristic leaching procedure (TCLP) and simple bioaccessibility extraction test (SBET). In the study, Hakason index, Nemerow index ( P), the hazard index ( HI) and the cancer risk index ( RI) were calculated to assess the potential risk. The sequence of potential ecological risk based on Hakason index was arsenic (As) > cadmium (Cd) > lead (Pb) > copper (Cu) > chromium (Cr), in particular, As and Cd were regarded as high polluted metals. While the results of extraction of TCLP were assessed using P, the sequence was As > Pb > Cd > Cr > Cu, which mean that As and Pb should be low polluted, and Cd, Cr and Cu would barely not polluted. For human health, total carcinogenic risk for children and adults was 2.01×10 −3 and 1.05×10 −3, respectively. This could be considered to be intolerable in urban street dust exposure. The sequence in the hazard quotient ( HQ) of each element was As > Cr > Pb > Cu > Cd. The HI value of these toxic metals in urban street dust for children and adults was 5.88×10 −1 and 2.80×10 −1, respectively. According to the characters of chemistry, mobility, and bioavailability of metals in urban street dust, we estimated the hazards on the environment and human health, which will help us to get more reasonable information for risk management of metals in urban environment.

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          Most cited references23

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          Multivariate analysis of heavy metal contamination in urban dusts of Xi'an, Central China.

          Though there are many studies of heavy metal contaminations of urban dusts in developed countries, little attention has been paid to this kind of study in developing countries, including China. Therefore, a series of investigations were performed to provide heavy metal signatures of urban dusts and to evaluate potential sources in Xi'an, Shaanxi Province. Sixty-five samples of urban dusts were collected in Xi'an. Then Ag, Cr, Cu, Mn, Pb and Zn concentrations were determined by using atomic absorption spectrophotometry, and As, Hg and Sb concentrations by atomic fluorescence spectroscopy. The results indicate that, in comparison with Chinese soil, urban dusts in Xi'an have elevated metal concentrations as a whole, except those of arsenic and manganese. These concentration levels are comparable to those in other studies. Correlation coefficient analysis, principal component analysis (PCA) and cluster analysis (CA) were performed and three main sources with corresponding cluster elements were identified: (1) Ag and Hg have commercial and domestic sources; (2) Cr, Cu, Pb, Sb and Zn are mainly derived from industrial sources, combined with traffic sources as well for Pb and Zn; (3) As and Mn come mainly from soil sources, and As also has an industrial source. Based on PCA and CA analyses, manganese was selected as the reference element, and heavy metal enrichment factors (Efs) were calculated, which in turn further confirms the source identification. Also, Efs give an insight of human influence degree of urban dusts.
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            Spatial, sources and risk assessment of heavy metal contamination of urban soils in typical regions of Shenyang, China.

            Surface soil samples from 36 sampling sites including different functional areas in seven districts of Shenyang, China were collected and analyzed. The results showed that the average concentrations of Cd, Cu, Pb and Zn in soil of Shenyang were up to 0.42, 51.26, 75.29 and 140.02mg/kg, respectively, which are much higher than their natural background values. Among the functional areas and administrative regions, the industrial regions and the Tiexi District displayed the highest metal concentrations. Pearson's correlation analysis showed that there existed close correlations among Cd, Cu, Pb and Zn (except for Cd-Cu) at 1% level. Principal Component Analysis (PCA) coupled with correlation between heavy metals revealed that heavy metal contamination might originate from traffic and industrial activities. The values of pollution index (PI) and integrated pollution index (IPI) indicated that metal pollution level was Pb>Cd>Zn>Cu, and Cd, Cu, Pb and Zn belong to moderate or high pollution level. Potential ecological risk indexes (RI) further indicated that Shenyang was suffering from serious metal contamination. These results are important for the development of proper management strategies to decrease non-point source pollution by various remediation practices in Shenyang, China.
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              Comparison of five in vitro digestion models to study the bioaccessibility of soil contaminants.

              Soil ingestion can be a major exposure route for humans to many immobile soil contaminants. Exposure to soil contaminants can be overestimated if oral bioavailability is not taken into account. Several in vitro digestion models simulating the human gastrointestinal tract have been developed to assess mobilization of contaminants from soil during digestion, i.e., bioaccessibility. Bioaccessibility is a crucial step in controlling the oral bioavailability for soil contaminants. To what extent in vitro determination of bioaccessibility is method dependent has, until now, not been studied. This paper describes a multi-laboratory comparison and evaluation of five in vitro digestion models. Their experimental design and the results of a round robin evaluation of three soils, each contaminated with arsenic, cadmium, and lead, are presented and discussed. A wide range of bioaccessibility values were found for the three soils: for As 6-95%, 1-19%, and 10-59%; for Cd 7-92%, 5-92%, and 6-99%; and for Pb 4-91%, 1-56%, and 3-90%. Bioaccessibility in many cases is less than 50%, indicating that a reduction of bioavailability can have implications for health risk assessment. Although the experimental designs of the different digestion systems are distinct, the main differences in test results of bioaccessibility can be explained on the basis of the applied gastric pH. High values are typically observed for a simple gastric method, which measures bioaccessibility in the gastric compartment at low pHs of 1.5. Other methods that also apply a low gastric pH, and include intestinal conditions, produce lower bioaccessibility values. The lowest bioaccessibility values are observed for a gastrointestinal method which employs a high gastric pH of 4.0.
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                Author and article information

                Contributors
                Role: Editor
                Journal
                PLoS One
                PLoS ONE
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, USA )
                1932-6203
                2014
                20 March 2014
                : 9
                : 3
                : e92459
                Affiliations
                [1 ]Key Laboratory of Pollution Processes and Environmental Criteria (Ministry of Education), College of Environmental Science and Engineering, Nankai University, Tianjin, China
                [2 ]Department of Agricultural and Biological Engineering, University of Florida, Gainesville, Florida, United States of America
                The Ohio State University, United States of America
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Conceived and designed the experiments: QZ YW. Performed the experiments: BY. Analyzed the data: BY. Contributed reagents/materials/analysis tools: BY. Wrote the paper: BY. Guided the work as the supervisor and revised the manuscript many times: QZ. Improved the experimental scheme and made an elementary polishing and correction in English: YW.

                Article
                PONE-D-13-50564
                10.1371/journal.pone.0092459
                3961371
                24651129
                af3a6b5d-6e92-4bd0-ae50-b0238d5c8801
                Copyright @ 2014

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 9 December 2013
                : 21 February 2014
                Page count
                Pages: 9
                Funding
                This work was financially supported by the National Natural Science Foundation of China as a key project (grant No. 21037002) and the Ministry of Science and Technology, People′s Republic of China as a 863 project (grant No. 2012AA101403-2). The funders had no role in study design , data collection and analysis, decision to publish, or preparation of the manuscript.
                Categories
                Research Article
                Biology and Life Sciences
                Ecology
                Urban Ecology
                Toxicology
                Toxic Agents
                Toxins
                Heavy Metals
                Earth Sciences
                Geochemistry
                Biogeochemistry
                Ecology and Environmental Sciences
                Medicine and Health Sciences
                Health Care
                Environmental Health
                Public and Occupational Health
                Physical Sciences
                Chemistry
                Environmental Chemistry
                Pollutants
                Urban Runoff

                Uncategorized
                Uncategorized

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