Drug Testing in Blood: Validated Negative-Ion Chemical Ionization Gas Chromatographic-Mass Spectrometric Assay for Enantioselective Measurement of the Designer Drugs MDEA, MDMA, and MDA and Its Application to Samples from a Controlled Study with MDMA

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Abstract

The enantiomers of the designer drugs 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA), and 3,4-methylenedioxyethylamphetamine (MDEA) differ in their pharmacologic and toxicologic potency. The aim of this study was to develop an assay for measuring these enantiomers in small plasma volumes and to analyze samples from a controlled study with MDMA.

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Journal

Title: Clinical Chemistry

Abbreviated Title: Clinical Chemistry

Publisher: American Association for Clinical Chemistry (AACC)

ISSN (Print): 0009-9147

ISSN (Electronic): 1530-8561

Publication date Created: October 01 2005

Publication date (Print): October 01 2005

Volume: 51

Issue: 10

Pages: 1811-1822

Article

DOI: 10.1373/clinchem.2005.052746

PubMed ID: 16099938

SO-VID: af689116-825d-48c9-a55a-fe2c276402ca

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