Katharina Timper 1 , Wiebke Fenske 1 , Felix Kühn 1 , Nica Frech 1 , Birsen Arici 1 , Jonas Rutishauser 1 , Peter Kopp 1 , Bruno Allolio 1 , Christoph Stettler 1 , Beat Müller 1 , Mira Katan 1 , Mirjam Christ-Crain 1
The polyuria-polydipsia syndrome comprises primary polydipsia (PP) and central and nephrogenic diabetes insipidus (DI). Correctly discriminating these entities is mandatory, given that inadequate treatment causes serious complications. The diagnostic "gold standard" is the water deprivation test with assessment of arginine vasopressin (AVP) activity. However, test interpretation and AVP measurement are challenging.