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      Digital phenotyping for mental health of college students: a clinical review

      review-article
      , ,
      Evidence-Based Mental Health
      BMJ Publishing Group
      adult psychiatry, depression & mood disorders

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          Abstract

          Experiencing continued growth in demand for mental health services among students, colleges are seeking digital solutions to increase access to care as classes shift to remote virtual learning during the COVID-19 pandemic. Using smartphones to capture real-time symptoms and behaviours related to mental illnesses, digital phenotyping offers a practical tool to help colleges remotely monitor and assess mental health and provide more customised and responsive care. This narrative review of 25 digital phenotyping studies with college students explored how this method has been deployed, studied and has impacted mental health outcomes. We found the average duration of studies to be 42 days and the average enrolled to be 81 participants. The most common sensor-based streams collected included location, accelerometer and social information and these were used to inform behaviours such as sleep, exercise and social interactions. 52% of the studies included also collected smartphone survey in some form and these were used to assess mood, anxiety and stress among many other outcomes. The collective focus on data that construct features related to sleep, activity and social interactions indicate that this field is already appropriately attentive to the primary drivers of mental health problems among college students. While the heterogeneity of the methods of these studies presents no reliable target for mobile devices to offer automated help—the feasibility across studies suggests the potential to use these data today towards personalising care. As more unified digital phenotyping research evolves and scales to larger sample sizes, student mental health centres may consider integrating these data into their clinical practice for college students.

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          Most cited references36

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          Is Open Access

          New Tools for New Research in Psychiatry: A Scalable and Customizable Platform to Empower Data Driven Smartphone Research

          Background A longstanding barrier to progress in psychiatry, both in clinical settings and research trials, has been the persistent difficulty of accurately and reliably quantifying disease phenotypes. Mobile phone technology combined with data science has the potential to offer medicine a wealth of additional information on disease phenotypes, but the large majority of existing smartphone apps are not intended for use as biomedical research platforms and, as such, do not generate research-quality data. Objective Our aim is not the creation of yet another app per se but rather the establishment of a platform to collect research-quality smartphone raw sensor and usage pattern data. Our ultimate goal is to develop statistical, mathematical, and computational methodology to enable us and others to extract biomedical and clinical insights from smartphone data. Methods We report on the development and early testing of Beiwe, a research platform featuring a study portal, smartphone app, database, and data modeling and analysis tools designed and developed specifically for transparent, customizable, and reproducible biomedical research use, in particular for the study of psychiatric and neurological disorders. We also outline a proposed study using the platform for patients with schizophrenia. Results We demonstrate the passive data capabilities of the Beiwe platform and early results of its analytical capabilities. Conclusions Smartphone sensors and phone usage patterns, when coupled with appropriate statistical learning tools, are able to capture various social and behavioral manifestations of illnesses, in naturalistic settings, as lived and experienced by patients. The ubiquity of smartphones makes this type of moment-by-moment quantification of disease phenotypes highly scalable and, when integrated within a transparent research platform, presents tremendous opportunities for research, discovery, and patient health.
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            Digital Phenotyping

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              The digital phenotype.

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                Author and article information

                Journal
                Evid Based Ment Health
                Evid Based Ment Health
                ebmental
                ebmh
                Evidence-Based Mental Health
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                1362-0347
                1468-960X
                November 2020
                30 September 2020
                30 September 2020
                : 23
                : 4
                : 161-166
                Affiliations
                [1] departmentDivision of Digital Psychiatry , Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, Massachusetts, USA
                Author notes
                [Correspondence to ] Dr John Torous, Psychiatry, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; jtorous@ 123456bidmc.harvard.edu
                Author information
                http://orcid.org/0000-0002-5362-7937
                Article
                ebmental-2020-300180
                10.1136/ebmental-2020-300180
                10231503
                32998937
                b34ab6d9-0c9a-4432-b6ea-24c86ae6492c
                © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

                This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.

                History
                : 04 August 2020
                : 02 September 2020
                : 03 September 2020
                Categories
                Clinical Review
                1507
                2474
                Custom metadata
                editors-choice
                free

                Clinical Psychology & Psychiatry
                adult psychiatry,depression & mood disorders
                Clinical Psychology & Psychiatry
                adult psychiatry, depression & mood disorders

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