+1 Recommend
0 collections
      • Record: found
      • Abstract: found
      • Article: not found

      Sentinel surveillance for influenza and other respiratory viruses in Côte d’Ivoire, 2003–2010


      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          Background  Many countries in Africa have lacked sentinel surveillance systems for influenza and are under‐represented in data used for global vaccine strain selection.

          Objectives  We describe 8 years of sentinel surveillance data and the contribution of influenza and other viruses to medically attended influenza‐like illness (ILI) in Côte d’Ivoire.

          Methods  Sentinel surveillance was established in 2003. Nasopharyngeal (NP) specimens and epidemiologic data are collected from persons of all ages presenting with ILI at sentinel sites. Respiratory specimens have been tested for influenza using various viral and molecular diagnostic methods. A subset of 470 specimens collected from children aged 0–5 years were tested for multiple respiratory viruses using RT‐PCR.

          Results  From 2003 to 2010, 5074 NP specimens were collected from patients with ILI. Overall, 969/5074 (19%) of these specimens tested positive for influenza. Seasonal influenza A(H1N1) viruses predominated during 5 years and influenza A(H3N2) viruses predominated during 3 years. Influenza B viruses cocirculated with influenza A viruses during each year from 2004 to 2010. Seasonal peaks in influenza circulation were observed during the months of May, June, and October, with the largest peak corresponding with the primary rainfall season. Of 470 specimens collected from children under aged 5 who were tested for multiple respiratory viruses, a viral respiratory pathogen was detected in 401/470 (85%) of specimens. Commonly detected viruses were RSV (113 of 470 specimens, 24%), rhinoviruses (85/470, 18%), influenza (77/470, 16%), and parainfluenza (75/470, 16%).

          Conclusion  In Côte d’Ivoire, there is a significant annual contribution of influenza and other respiratory viruses to medically attended ILI.

          Related collections

          Most cited references18

          • Record: found
          • Abstract: found
          • Article: not found

          Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus.

          In May, 1997, a 3-year-old boy in Hong Kong was admitted to the hospital and subsequently died from influenza pneumonia, acute respiratory distress syndrome, Reye's syndrome, multiorgan failure, and disseminated intravascular coagulation. An influenza A H5N1 virus was isolated from a tracheal aspirate of the boy. Preceding this incident, avian influenza outbreaks of high mortality were reported from three chicken farms in Hong Kong, and the virus involved was also found to be of the H5 subtype. We carried out an antigenic and molecular comparison of the influenza A H5N1 virus isolated from the boy with one of the viruses isolated from outbreaks of avian influenza by haemagglutination-inhibition and neuraminidase-inhibition assays and nucleotide sequence analysis. Differences were observed in the antigenic reactivities of the viruses by the haemagglutination-inhibition assay. However, nucleotide sequence analysis of all gene segments revealed that the human virus A/Hong Kong/156/97 was genetically closely related to the avian A/chicken/Hong Kong/258/97. Although direct contact between the sick child and affected chickens has not been established, our results suggest transmission of the virus from infected chickens to the child without another intermediate mammalian host acting as a "mixing vessel". This event illustrates the importance of intensive global influenza surveillance.
            • Record: found
            • Abstract: not found
            • Article: not found

            Update on avian influenza A (H5N1) virus infection in humans.

              • Record: found
              • Abstract: not found
              • Article: not found

              Community-acquired pneumonia in children.


                Author and article information

                Influenza Other Respir Viruses
                Influenza Other Respir Viruses
                Influenza and Other Respiratory Viruses
                Blackwell Publishing Ltd (Oxford, UK )
                02 August 2012
                May 2013
                : 7
                : 3 ( doiID: 10.1111/irv.2013.7.issue-3 )
                : 296-303
                [ 1 ]Respiratory virus unit, Department of epidemic virus and National Influenza Centre, Pasteur Institute, Abidjan, Côte d’Ivoire.
                [ 2 ]Institut National de l’Hygiène Publique, Service de la surveillance èpidèmiologique, Abidjan, Côte d’Ivoire.
                [ 3 ]Influenza Division, Centers for Disease Control and Prevention, Accra, Ghana.
                [ 4 ]U.S. Naval Medical Research Unit No.3 (NAMRU‐3/GDDRP) Noguchi Memorial Institute for Medical Research (NMIMR).
                [ 5 ]Division vaccins, Sanofi Aventis – Pasteur, Abidjan, Côte d’Ivoire.
                [ 6 ]Institut Pasteur de Paris, Direction des affaires Internationales, Paris, France.
                [ 7 ]Influenza Program Director, U.S. Centers for Disease Control and Prevention, Nairobi, Kenya.
                Author notes
                [*]Hervé A. Kadjo, National Influenza Centre, Respiratory Virus Unit, Department of Epidemic Virus, Pasteur Institute, Côte d’Ivoire 01, BP 490 Abidjan 01, Côte d’Ivoire. E‐mail: rvkdjo@ 123456yahoo.fr
                © 2012 Blackwell Publishing Ltd
                Page count
                Figures: 3, Tables: 3, Pages: 8
                Part 1
                Original Articles
                Original Article
                Custom metadata
                May 2013
                Converter:WILEY_ML3GV2_TO_NLMPMC version:4.6.9 mode:remove_FC converted:04.11.2015

                Infectious disease & Microbiology
                côte d’ivoire,influenza viruses,respiratory viruses,sentinel surveillance


                Comment on this article


                Similar content600

                Cited by18

                Most referenced authors494