The PARAGON Heart Failure trial - ongoing investigation of the angiotensin receptor antagonist/neprilysin inhibitor sacubitril/valsartan in heart failure patients with hypertension and preserved ejection fraction.

[1 ] a Department of Cardiology , University of Oslo , Ullevaal Hospital , Oslo , Norway.

[2 ] b Department of Hypertension and Diabetology , Medical University of Gdansk , Gdansk , Poland.

[3 ] c Service of Nephrology and Hypertension , Centre Hospitalier Universitaire Vaudois , Lausanne , Switzerland.

[4 ] d Vascular Biology and Hypertension Program, Department of Medicine , University of Alabama at Birmingham , Birmingham , AL , USA.