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      Total knee arthroplasty: indication of blood transfusion according to hematimetric variation and clinical symptoms of hypoperfusion ☆☆ Translated title: Artroplastia total do joelho: indicação de transfusão sanguínea de acordo com a variação hematimétrica e os sintomas clínicos de hipoperfusão

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          Abstract

          Objective

          To analyze the relationship between hematimetric variation and the presence of clinical symptoms of hypoperfusion for indicating blood transfusion in patients undergoing total knee arthroplasty.

          Methods

          A retrospective analysis was conducted on data gathered from the medical files of 55 patients with a diagnosis of gonarthrosis, who underwent total knee arthroplasty at a hospital orthopedics and traumatology service between February 2011 and December 2012. The patients studied presented unilateral joint degeneration and fitted into the indications for surgical treatment. All the patients underwent a preoperative cardiological evaluation, presenting a pattern of ASA I–III and absence of blood dyscrasia, and preoperative hemoglobin measurements were made. However, no minimum hematimetric value was established for the surgical treatment; there were only clinical criteria for blood perfusion.

          Results

          Among the 55 patients, 35 were female and 20 were male, and the mean age was 68 years. Six patients underwent homologous blood transfusion, because of their clinical condition of tissue hypoperfusion, persistent hypotension, loss of consciousness, sweating and coercible vomiting. They presented postoperative hemoglobin of 7.5–8.8 g/dL.

          Conclusion

          For patients with falls in hemoglobin counts greater than 20% and values lower than 9 g/dL after the surgery, there is a possible need for blood transfusion, which should only be indicated when accompanied by major symptoms of tissue hypoperfusion.

          Resumo

          Objetivo

          Analisar a relação entre a variação hematimétrica e a presença de sintomas clínicos de hipoperfusão para a indicação de transfusão sanguínea em pacientes submetidos a artroplastia total do joelho.

          Métodos

          Fez-se uma análise retrospectiva dos dados coletados nos prontuários de 55 pacientes com diagnóstico de gonartrose submetidos a artroplastia unilateral total do joelho feita pelo serviço de ortopedia e traumatologia de um hospital de fevereiro de 2011 a dezembro de 2012. Os pacientes estudados apresentaram degeneração articular unilateral e se enquadraram na indicação para o tratamento cirúrgico. Todos foram submetidos a avaliação pré-operatória cardiológica e manteve-se um padrão correspondente a ASA-I até III, ausência de discrasia sanguínea e mensuração de hemoglobina pré-operatória. Porém, não foi estabelecido valor hematimétrico mínimo para o tratamento cirúrgico, apenas critérios clínicos de perfusão sanguínea.

          Resultados

          Dos 55 pacientes, 35 do sexo feminino e 20 do masculino, com média de 68 anos, apenas seis foram submetidos a transfusão sanguínea homóloga, decorrente do quadro clínico de hipoperfusão tecidual, hipotensão persistente, perda da consciência, sudorese e vômitos coercíveis e apresentaram hemoglobina pós-operatória entre 7,5 e 8,8 g/dL.

          Conclusão

          Pacientes com queda acima de 20% na contagem de hemoglobina e valores abaixo de 9 g/dL após a cirurgia sugerem uma possível necessidade de transfusão sanguínea, que só deve ser indicada quando acompanhada de sintomas maiores de hipoperfusão tecidual.

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          Most cited references34

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          An analysis of blood management in patients having a total hip or knee arthroplasty.

          Three hundred and thirty orthopaedic surgeons in the United States participated in a study of transfusion requirements associated with total joint arthroplasty. A total of 9482 patients (3920 patients who had a total hip replacement and 5562 patients who had a total knee replacement) were evaluated prospectively from September 1996 through June 1997. Of those patients, 4409 (46 percent [57 percent of the patients who had a hip replacement and 39 percent of the patients who had a knee replacement]) had a blood transfusion. Two thousand eight hundred and ninety patients (66 percent) received autologous blood, and 1519 patients (34 percent) received allogenic blood. Ordered logistic regression analysis showed the most important predictors of the transfusion of allogenic blood to be a low baseline hemoglobin level and a lack of predonated autologous blood. Preoperative donation of autologous blood decreases the risk of transfusion of allogenic blood; however, inefficiencies in the procedures for obtaining autologous blood were identified. Sixty-one percent (5741) of the patients had predonated blood for autologous transfusion, but 4464 (45 percent) of the 9920 units of the predonated autologous blood were not used. Primary procedures and revision total knee arthroplasty were associated with the greatest number of wasted autologous units. Of the 5741 patients who had predonated blood, 503 (9 percent) needed a transfusion of allogenic blood. The frequency of allogenic blood transfusion varied with respect to the type of operative procedure (revision total hip arthroplasty and bilateral total knee arthroplasty were associated with the highest prevalence of such transfusions) and with a baseline hemoglobin level of 130 grams per liter or less. Transfusion of allogenic blood was also associated with infection (p < or = 0.001), fluid overload (p < or = 0.001), and increased duration of hospitalization (p < or = 0.01). These latter findings warrant further evaluation in controlled studies.
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            • Article: not found

            Differences in short-term complications between spinal and general anesthesia for primary total knee arthroplasty.

            Spinal anesthesia has been associated with lower postoperative rates of deep-vein thrombosis, a shorter operative time, and less blood loss when compared with general anesthesia. The purpose of the present study was to identify differences in thirty-day perioperative morbidity and mortality between anesthesia choices among patients undergoing total knee arthroplasty.
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              • Article: not found

              Effects of tourniquet use on blood loss and soft-tissue damage in total knee arthroplasty: a randomized controlled trial.

              Although tourniquets are widely used in total knee arthroplasty, their effectiveness in reducing blood loss and their influence on the postoperative course remain unclear. Tourniquet-related soft-tissue damage is a related concern. We performed a prospective, randomized, controlled trial to clarify the effect of tourniquets in total knee arthroplasty. Seventy-two patients undergoing total knee arthroplasty were randomly allocated to a tourniquet or non-tourniquet group. Blood loss and changes in C-reactive protein, creatine phosphokinase, and other indicators of soft-tissue damage were monitored preoperatively and postoperatively on Days 1, 2, and 4. Thigh pain, knee pain, limb swelling, rehabilitation progress, and hospital stays were also recorded for comparison. Patients in the tourniquet group showed smaller decreases in hemoglobin (mean and standard deviation, 2.6 ± 0.9 versus 3.7 ± 1.3 g/dL) and hematocrit (7.6% ± 2.8% versus 10.4% ± 4.0%), less calculated blood loss (303 ± 119 versus 423 ± 197 mL), and smaller increases in C-reactive protein (peak value, 175 ± 55 versus 139 ± 75 mg/dL) and creatine phosphokinase (peak value, 214 ± 89 versus 162 ± 104 U/L) compared with those in the non-tourniquet group. There was slightly less postoperative pain in the non-tourniquet group. There were no significant differences between the groups in terms of swelling, rehabilitation progress, or hospital stays. The use of a tourniquet during total knee arthroplasty was effective for reducing blood loss and avoiding excessive postoperative inflammation and muscle damage. The use of a tourniquet was related to slightly more postoperative pain but did not affect postoperative recovery.
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                Author and article information

                Contributors
                Journal
                Rev Bras Ortop
                Rev Bras Ortop
                Revista Brasileira de Ortopedia
                Elsevier
                2255-4971
                13 August 2014
                Sep-Oct 2014
                13 August 2014
                : 49
                : 5
                : 507-512
                Affiliations
                [0005]Orthopedics and Traumatology Service, Hospital São Francisco, Ribeirão Preto, SP, Brazil
                Author notes
                [* ] Corresponding author. torradarodrigo@ 123456hotmail.com
                Article
                S2255-4971(14)00119-0
                10.1016/j.rboe.2013.09.002
                4487474
                26229853
                b69fd687-a9c5-4cf3-93b8-dc52de3ee9da
                © 2014 Sociedade Brasileira de Ortopedia e Traumatologia. Published by Elsevier Editora Ltda.

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 12 August 2013
                : 12 September 2013
                Categories
                Original Article

                hemoglobin,surgical blood loss,joints,arthroplasty,hypovolemia,hemoglobina,perda sanguínea cirúrgica,articulações,artroplastia,hipovolemia

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