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      Adipose Tissue Redistribution and Ectopic Lipid Deposition in Active Acromegaly and Effects of Surgical Treatment.

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          Abstract

          GH and IGF-I have important roles in the maintenance of substrate metabolism and body composition. However, when in excess in acromegaly, the lipolytic and insulin antagonistic effects of GH may alter adipose tissue (AT) deposition.

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          Author and article information

          Journal
          J. Clin. Endocrinol. Metab.
          The Journal of clinical endocrinology and metabolism
          The Endocrine Society
          1945-7197
          0021-972X
          Aug 2015
          : 100
          : 8
          Affiliations
          [1 ] Departments of Medicine (C.M.R.-V., W.S., J.C.F., D.G., P.U.F.), Radiology (H.M., F.A.-M.), Biostatistics (Z.J.), and Neurosurgery (J.N.B.), Columbia University, College of Physicians & Surgeons, New York, New York 10032; and Departments of Medicine and Neurosurgery (K.D.P.), Mt. Sinai School of Medicine, New York, New York 10029.
          Article
          10.1210/jc.2015-1917
          10.1210/jc.2015-1917
          4524994
          26037515
          ba69e3e5-3a6d-485d-a2e1-54ba5938e30f
          History

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