Demographics, laboratory parameters and outcomes of 1061 patients with COVID-19: A report from Tehran, Iran

Abstract

We aimed to determine the characteristics of coronavirus disease-2019 among the Iranian population. In this study, we collected and analyzed the demographics, laboratory findings and outcomes of patients with COVID-19 who were admitted to Masih Daneshvari Hospital in Tehran, Iran between February 20, 2020 and April 2, 2020. Of 1061 patients, the median age was 55 years (interquartile range [IQR], 44-66 years) and 692 (65.2%) were male. Among these, 129 (12.2%) patients died at some point during hospitalization in the ward or intensive care unit (ICU). From the remaining 932 survivors, 46 (5.0%) patients were admitted to the ICU and 886 (95.0%) patients were hospitalized in the ward. Patients who died were significantly older than those hospitalized in the ward (p<0.001). The median absolute number of lymphocytes was 1.2 × 10 ³ per microliter (IQR, 0.9-1.6 × 10 ³ per microliter) and 708 (66.7%) patients had lymphopenia (absolute lymphocyte count <1500 per microliter). Among the laboratory tests, D-dimer, serum ferritin and albumin had the strongest correlation with mortality (r = 0.455, r = 0.412, r = -0.406, respectively; p-values <0.001). Conclusively, laboratory findings could provide useful information in regard to the management of patients with COVID-19.