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      Minimally invasive access type related to outcomes of sutureless and rapid deployment valves

      research-article
      e1 , e2 , e3 , e4 , e5 , e6 , e7 , e8 , e9 , e10 , e11 , e12 , e13 , e14 , e5 , e15 , e16 , e17 , e18 , e19 , e20 , e10 , e14 , e1 , e2 , e14
      European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
      Oxford University Press
      Sutureless valve, Rapid deployment valve, Aortic valve replacement, Sutureless and Rapid Deployment Aortic Valve Replacement International Registry, The International Valvular Surgery Study Group

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          Abstract

          OBJECTIVES

          Minimally invasive surgical techniques with optimal outcomes are of paramount importance. Sutureless and rapid deployment aortic valves are increasingly implanted via minimally invasive approaches. We aimed to analyse the procedural outcomes of a full sternotomy (FS) compared with those of minimally invasive cardiac surgery (MICS) and further assess MICS, namely ministernotomy (MS) and anterior right thoracotomy (ART).

          METHODS

          We selected all isolated aortic valve replacements in the Sutureless and Rapid Deployment Aortic Valve Replacement International Registry (SURD-IR, n = 2257) and performed propensity score matching to compare aortic valve replacement through FS or MICS ( n = 508/group) as well as through MS and ART accesses ( n = 569/group).

          RESULTS

          Postoperative mortality was 1.6% in FS and MICS patients who had a mean logistic EuroSCORE of 11%. Cross-clamp and cardiopulmonary bypass (CPB) times were shorter in the FS group than in the MICS group (mean difference 3.2 and 9.2 min; P < 0.001). Patients undergoing FS had a higher rate of acute kidney injury (5.6% vs 2.8%; P = 0.012). Direct comparison of MS and ART revealed longer mean cross-clamp and CPB times (12 and 16.7 min) in the ART group ( P < 0.001). The postoperative outcome revealed a higher stroke rate (3.2% vs 1.2%; P = 0.043) as well as a longer postoperative intensive care unit [2 (1–3) vs 1 (1–3) days; P = 0.009] and hospital stay [11 (8–16) vs 8 (7–12) days; P < 0.001] in the MS group than in the ART group.

          CONCLUSIONS

          According to this non-randomized international registry, FS resulted in a higher rate of acute kidney injury. The ART access showed a lower stroke rate than MS and a shorter hospital stay than all other accesses. All these findings may be related to underlying patient risk factors.

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          Most cited references28

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          Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients

          Among patients with aortic stenosis who are at intermediate or high risk for death with surgery, major outcomes are similar with transcatheter aortic-valve replacement (TAVR) and surgical aortic-valve replacement. There is insufficient evidence regarding the comparison of the two procedures in patients who are at low risk.
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            Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients

            Transcatheter aortic-valve replacement (TAVR) is an alternative to surgery in patients with severe aortic stenosis who are at increased risk for death from surgery; less is known about TAVR in low-risk patients.
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              • Article: not found

              Ministernotomy versus conventional sternotomy for aortic valve replacement: a systematic review and meta-analysis.

              Most aortic valve replacements are by conventional full median sternotomy. Less invasive approaches have been developed with partial upper sternotomy (ministernotomy). Systematic review and meta-analysis were performed with studies comparing ministernotomy and full sternotomy for aortic valve replacement. Twenty-six studies were selected, with 4586 patients with aortic valve replacement (2054 ministernotomy, 2532 full sternotomy). There was no difference in mortality (odds ratio 0.71, 95% confidence interval 0.49-1.02). Ministernotomy had longer crossclamp and bypass times (weighted mean difference 7.90 minutes, 95% confidence interval 3.50-10.29 minutes, and 11.46 minutes, 95% confidence interval 5.26-17.65 minutes, respectively). Both intensive care unit and hospital stays were shorter with ministernotomy (weighted mean difference -0.46 days, 95% confidence interval -0.72 to -0.20 days, and -0.91 days, 95% confidence interval -1.45 to -0.37 days, respectively). Ministernotomy had shorter ventilation time and less blood loss within 24 hours (weighted mean difference -2.1 hours, 95% confidence interval -2.95 to -1.30 hours, and -79 mL, 95% confidence interval -23 to 136 mL, respectively). Randomized studies tended to demonstrate no difference between ministernotomy and full sternotomy. Rate of conversion from partial to conventional sternotomy was 3.0% (95% confidence interval 1.8%-.4%). Ministernotomy can be performed safely for aortic valve replacement, without increased risk of death or other major complication; however, few objective advantages have been shown. Surgeons must conduct well-designed, prospective studies of relevant, consistent clinical outcomes to determine the role of ministernotomy in cardiac surgery.
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                Author and article information

                Journal
                Eur J Cardiothorac Surg
                Eur J Cardiothorac Surg
                ejcts
                European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
                Oxford University Press
                1010-7940
                1873-734X
                November 2020
                26 June 2020
                26 June 2020
                : 58
                : 5
                : 1063-1071
                Affiliations
                [e1 ] Department of Cardiac Surgery, Medical University of Vienna , Vienna, Austria
                [e2 ] Cardiac Surgery Unit, Lancisi Cardiovascular Center, Polytechnic University of Marche , Ospedali Riuniti, Ancona, Italy
                [e3 ] Pasquinucci Heart Hospital , Massa, Italy
                [e4 ] Città di Lecce Hospital, GVM Care & Research , Cotignola, Italy
                [e5 ] Cardiovascular Center, Paracelsus Medical University , Nuremberg, Germany
                [e6 ] Department of Cardiac Surgery, University Heart Centre Dresden , Dresden, Germany
                [e7 ] Department of Cardiac Surgery, Henri Mondor University Hospital, Assistance Publique-Hôpitaux de Paris , Créteil, France
                [e8 ] Istituto Clinico Sant’Ambrogio, Clinical & Research Hospitals IRCCS Gruppo San Donato , Milan, Italy
                [e9 ] University Clinic for Cardiac Surgery, Leipzig Heart Center , Leipzig, Germany
                [e10 ] Department of Cardiothoracic Surgery, The Royal Prince Alfred Hospital , Sydney, Australia
                [e11 ] Cardiac Surgery Department, Sant’Orsola Malpighi Hospital, University of Bologna , Bologna, Italy
                [e12 ] Cardiovascular Surgery Unit, Maria Cecilia Hospital GVM Care & Research , Cotignola, Italy
                [e13 ] Cardiac Surgery Unit, Poliambulanza Foundation Hospital , Brescia, Italy
                [e14 ] The Collaborative Research (CORE) Group , Sydney, Australia
                [e15 ] Cardiac Surgery, Gasthuisberg, Cardiale Heelkunde , Leuven, Belgium
                [e16 ] Cardiovascular Department, Clinica San Gaudenzio , Novara, Italy
                [e17 ] Southlake Regional Health Centre , Newmarket, ON, Canada
                [e18 ] Department for the Treatment and Study of Cardiothoracic Diseases, Cardiothoracic Transplantation IRCCS-ISMETT , Palermo, Italy
                [e19 ] Division of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School , Hannover, Germany
                [e20 ] Department of Cardiovascular Surgery, University Hospital, University of Bern , Bern, Switzerland
                Author notes
                Corresponding author. Department of Cardiac Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Tel: +43-1-4040052620; e-mail: dr.andreas@ 123456me.com (M. Andreas).
                Author information
                http://orcid.org/0000-0003-4950-5432
                http://orcid.org/0000-0003-3662-0415
                http://orcid.org/0000-0001-8202-7570
                http://orcid.org/0000-0003-4197-7486
                http://orcid.org/0000-0003-3446-7832
                http://orcid.org/0000-0001-9781-3590
                http://orcid.org/0000-0003-4359-1261
                http://orcid.org/0000-0002-6975-8149
                http://orcid.org/0000-0001-7257-110X
                Article
                ezaa154
                10.1093/ejcts/ezaa154
                7577292
                32588056
                c061270e-11b2-4f39-8a84-098e9c7cd638
                © The Author(s) 2020. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

                History
                : 01 December 2019
                : 1 April 2020
                : 3 April 2020
                Page count
                Pages: 9
                Categories
                Conventional Valve Operations
                Eacts/117
                Eacts/125
                AcademicSubjects/MED00920

                Surgery
                sutureless valve,rapid deployment valve,aortic valve replacement,sutureless and rapid deployment aortic valve replacement international registry,the international valvular surgery study group

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