Metabolomic profiling of asthma and chronic obstructive pulmonary disease: A pilot study differentiating diseases.

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Abstract

Differentiating asthma from other causes of chronic airflow limitation, such as chronic obstructive pulmonary disease (COPD), can be difficult in a typical outpatient setting. The inflammation of asthma typically is different than that of COPD, and the degree of inflammation and cellular damage varies with asthma severity. Metabolomics is the study of molecules created by cellular metabolic pathways.

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Journal

Journal ID (iso-abbrev): J. Allergy Clin. Immunol.

Title: The Journal of allergy and clinical immunology

Publisher: Elsevier BV

ISSN (Electronic): 1097-6825

ISSN (Print): 0091-6749

Publication date (Electronic): Sep 2015

Volume: 136

Issue: 3

Affiliations

[1 ] Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada; Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; Department of Pediatrics, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. Electronic address: darryl.adamko@usask.ca.

[2 ] Department of Medicine, McMaster University, and St Joseph's Healthcare, Hamilton, Ontario, Canada.

[3 ] Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

[4 ] Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.

[5 ] Department of Emergency Medicine, University of Alberta, Edmonton, Alberta, Canada; School of Public Health, University of Alberta, Edmonton, Alberta, Canada.

Article

Publisher Item ID: S0091-6749(15)00728-9

DOI: 10.1016/j.jaci.2015.05.022

PubMed ID: 26152317

SO-VID: c2549a8d-ab5e-4c20-a9fb-2ab467f8dec6

History

Keywords: urine,nuclear magnetic resonance spectroscopy,chronic obstructive pulmonary disease,biomarkers,asthma,Metabolomics

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Keywords: urine, nuclear magnetic resonance spectroscopy, chronic obstructive pulmonary disease, biomarkers, asthma, Metabolomics

Metabolomic profiling of asthma and chronic obstructive pulmonary disease: A pilot study differentiating diseases.

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Abstract

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Biomarkers for Inflammatory Lung Disease

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