The partial faunal reserve of Pama is situated in the province of Kompienga, in the South-East of Burkina Faso, with typical Sudanian savanna vegetation. Adjacent to the Arli National Park and the Pendjari National Park, it is part of the so-called WAP complex, one of the largest wildlife areas in West Africa. Up to now, only little has been known about its flora. The present study aimed at reducing this gap in knowledge, and represents an important tool for conservation and research. The list of species was compiled from the surveys carried out from 2001 to 2004, additional relevé data, and herbarium specimens. We found 450 species, which belong to 244 genera and 73 families. The most species-rich family is Poaceae (83 species), followed by Fabaceae (64), Cyperaceae (24), Rubiaceae (22), Euphor- biaceae (20), Combretaceae (15), Asteraceae (14), Caesalpiniaceae (14), Mimosaceae (12), and Convolvulaceae (11).