Risk-reducing mastectomy in BRCA1/2 mutation carriers: factors influencing uptake and timing.

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Abstract

Strategies in case of high risk of breast cancer in BRCA1/2 mutation carriers are either intensive breast cancer screening or risk-reducing mastectomy (RRM). Both options have a high physical and psychosexual impact. The aim of this study is to investigate who chooses when to undergo RRM.

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Journal

Journal ID (iso-abbrev): Maturitas

Title: Maturitas

Publisher: Elsevier BV

ISSN (Electronic): 1873-4111

ISSN (Print): 0378-5122

Publication date (Electronic): Feb 2014

Volume: 77

Issue: 2

Affiliations

[1 ] Departments of Epidemiology, University Medical Center, University of Groningen, Groningen, The Netherlands. Electronic address: cmg.driel@umcg.nl.

[2 ] Reconstructive Surgery, University Medical Center, University of Groningen, Groningen, The Netherlands.

[3 ] Surgery, University Medical Center, University of Groningen, Groningen, The Netherlands.

[4 ] Medical Psychology, University Medical Center, University of Groningen, Groningen, The Netherlands.

[5 ] Genetics and University Medical Center, University of Groningen, Groningen, The Netherlands.

[6 ] Gynaecology, University Medical Center, University of Groningen, Groningen, The Netherlands.

[7 ] Departments of Epidemiology, University Medical Center, University of Groningen, Groningen, The Netherlands. Electronic address: g.h.de.bock@umcg.nl.

Article

Publisher Item ID: S0378-5122(13)00328-9

DOI: 10.1016/j.maturitas.2013.10.017

PubMed ID: 24268650

SO-VID: c8b07526-da4e-4443-8963-87e860339685

History

Keywords: Breast neoplasms/prevention & control,Genes, BRCA1,Genes, BRCA2,Mastectomy,Risk reduction behavior,Time factors

Data availability:

Keywords: Breast neoplasms/prevention & control, Genes, BRCA1, Genes, BRCA2, Mastectomy, Risk reduction behavior, Time factors

Risk-reducing mastectomy in BRCA1/2 mutation carriers: factors influencing uptake and timing.

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