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      Bifunctionalized mesoporous silica-supported gold nanoparticles: intrinsic oxidase and peroxidase catalytic activities for antibacterial applications.

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          Abstract

          Bifunctionalized mesoporous silica-supported gold nanoparticles as oxidase and peroxidase mimics for antibacterial applications are demonstrated. For the first time, these mesoporous silica-supported gold nanoparticles are applied as oxidase and peroxidase mimics. Taking advantage of their prominent enzyme activities, the MSN-AuNPs show excellent antibacterial properties against both Gram-negative and Gram-positive bacteria. Furthermore, MSN-AuNPs also exhibit outstanding performance in biofilm elimination .

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          Author and article information

          Journal
          Adv. Mater. Weinheim
          Advanced materials (Deerfield Beach, Fla.)
          Wiley-Blackwell
          1521-4095
          0935-9648
          Feb 11 2015
          : 27
          : 6
          Affiliations
          [1 ] State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Changchun, 130022, China; Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Changchun, 130022, China.
          Article
          10.1002/adma.201405105
          25655182
          c9421b03-8395-4ac0-9da6-4036315969e0
          History

          mesoporous silica,oxidase and peroxidase catalytic activities,antibacterial agents,bifunctionalization,gold nanoparticles

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