Metabolic tumour volumes measured at staging in lymphoma: methodological evaluation on phantom experiments and patients.

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Abstract

The presence of a bulky tumour at staging on CT is an independent prognostic factor in malignant lymphomas. However, its prognostic value is limited in diffuse disease. Total metabolic tumour volume (TMTV) determined on (18)F-FDG PET/CT could give a better evaluation of the total tumour burden and may help patient stratification. Different methods of TMTV measurement established in phantoms simulating lymphoma tumours were investigated and validated in 40 patients with Hodgkin lymphoma and diffuse large B-cell lymphoma.

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Journal

Journal ID (iso-abbrev): Eur. J. Nucl. Med. Mol. Imaging

Title: European journal of nuclear medicine and molecular imaging

ISSN (Electronic): 1619-7089

ISSN (Print): 1619-7070

Publication date (Electronic): Jun 2014

Volume: 41

Issue: 6

Affiliations

[1 ] Department of Nuclear Medicine, Hôpital Henri Mondor and Paris-Est University, Créteil, France, michel.meignan@hmn.aphp.fr.

Article

DOI: 10.1007/s00259-014-2705-y

PubMed ID: 24570094

SO-VID: c953c7c4-132e-4239-9dcc-6299801613bc

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