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Accelerated radiotherapy, carbogen and nicotinamide (ARCON) in locally advanced head and neck cancer: a feasibility study
Michele I. Saunders ,
Peter J. Hoskin ,
Katherine Pigott ,
Melanie E.B. Powell ,
Kathleen Goodchild ,
Stan Dische ,
Juliana Denekamp ,
Michael R.L. Stratford ,
Madeleine F. Dennis ,
Ana Maria Rojas
November 1997
November 1997
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Abstract
ARCON (Accelerated Radiotherapy, CarbOgen, Nicotinamide) achieves a large therapeutic
gain in rodents. A phase I/II study was therefore undertaken to determine its feasibility
in patients with locally advanced head and neck cancer.