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      Models of Integration of Specialized Palliative Care with Oncology

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          Opinion statement

          Evidence from randomized controlled trials and meta-analyses has shown that early integration of specialized palliative care improves symptoms and quality of life for patients with advanced cancer. There are various models of early integration, which may be classified based on setting of care and method of palliative care referral. Most successful randomized controlled trials of early palliative care have used a model of specialized teams providing in-person palliative care in free-standing or embedded outpatient clinics. During the COVID-19 pandemic, telehealth has become a prominent model for palliative care delivery. This model of care has been well received by patients and palliative care providers, although evidence to date is limited. Despite evidence from trials that routine early integration of palliative care into oncology care improves patient outcomes, referral to palliative care still occurs mostly according to the judgment of individual oncologists. This hinders equitable access to palliative care and to its known benefits for patients and their caregivers. Automated referral based on triggering criteria is being actively explored as an alternative. In particular, routine technology-assisted symptom screening, combined with targeted needs-based automatic referral to outpatient palliative care, may improve integration and ultimately increase quality of life.

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          Most cited references89

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          Early palliative care for patients with metastatic non-small-cell lung cancer.

          Patients with metastatic non-small-cell lung cancer have a substantial symptom burden and may receive aggressive care at the end of life. We examined the effect of introducing palliative care early after diagnosis on patient-reported outcomes and end-of-life care among ambulatory patients with newly diagnosed disease. We randomly assigned patients with newly diagnosed metastatic non-small-cell lung cancer to receive either early palliative care integrated with standard oncologic care or standard oncologic care alone. Quality of life and mood were assessed at baseline and at 12 weeks with the use of the Functional Assessment of Cancer Therapy-Lung (FACT-L) scale and the Hospital Anxiety and Depression Scale, respectively. The primary outcome was the change in the quality of life at 12 weeks. Data on end-of-life care were collected from electronic medical records. Of the 151 patients who underwent randomization, 27 died by 12 weeks and 107 (86% of the remaining patients) completed assessments. Patients assigned to early palliative care had a better quality of life than did patients assigned to standard care (mean score on the FACT-L scale [in which scores range from 0 to 136, with higher scores indicating better quality of life], 98.0 vs. 91.5; P=0.03). In addition, fewer patients in the palliative care group than in the standard care group had depressive symptoms (16% vs. 38%, P=0.01). Despite the fact that fewer patients in the early palliative care group than in the standard care group received aggressive end-of-life care (33% vs. 54%, P=0.05), median survival was longer among patients receiving early palliative care (11.6 months vs. 8.9 months, P=0.02). Among patients with metastatic non-small-cell lung cancer, early palliative care led to significant improvements in both quality of life and mood. As compared with patients receiving standard care, patients receiving early palliative care had less aggressive care at the end of life but longer survival. (Funded by an American Society of Clinical Oncology Career Development Award and philanthropic gifts; ClinicalTrials.gov number, NCT01038271.)
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            Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial.

            There is growing interest to enhance symptom monitoring during routine cancer care using patient-reported outcomes, but evidence of impact on clinical outcomes is limited.
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              Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update

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                Author and article information

                Contributors
                camilla.zimmermann@uhn.on.ca
                Journal
                Curr Treat Options Oncol
                Curr Treat Options Oncol
                Current Treatment Options in Oncology
                Springer US (New York )
                1527-2729
                1534-6277
                8 April 2021
                2021
                : 22
                : 5
                : 44
                Affiliations
                [1 ]GRID grid.415224.4, ISNI 0000 0001 2150 066X, Department of Supportive Care, , Princess Margaret Cancer Centre, University Health Network, ; 610 University Ave., 16-712, Toronto, Ontario M5G 2M9 Canada
                [2 ]GRID grid.17063.33, ISNI 0000 0001 2157 2938, Divisions of Palliative Medicine and Medical Oncology, , University of Toronto, ; Toronto, Canada
                [3 ]GRID grid.17063.33, ISNI 0000 0001 2157 2938, Department of Medicine, , University of Toronto, ; Toronto, Canada
                Author information
                http://orcid.org/0000-0003-4889-0244
                Article
                836
                10.1007/s11864-021-00836-1
                8027976
                33830352
                c9e0b932-2290-4980-b8a5-f0df7a12d650
                © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                : 18 February 2021
                Categories
                Palliative and Supportive Care (MP Davis, Section Editor)
                Custom metadata
                © Springer Science+Business Media, LLC, part of Springer Nature 2021

                Oncology & Radiotherapy
                palliative care,oncology,neoplasms,quality of life,telemedicine,models of care,integration,integrated healthcare systems

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