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      Methods of the 7 th National Audit Project (NAP7) of the Royal College of Anaesthetists: peri‐operative cardiac arrest

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          Summary

          Cardiac arrest in the peri‐operative period is rare but associated with significant morbidity and mortality. Current reporting systems do not capture many such events, so there is an incomplete understanding of incidence and outcomes. As peri‐operative cardiac arrest is rare, many hospitals may only see a small number of cases over long periods, and anaesthetists may not be involved in such cases for years. Therefore, a large‐scale prospective cohort is needed to gain a deep understanding of events leading up to cardiac arrest, management of the arrest itself and patient outcomes. Consequently, the Royal College of Anaesthetists chose peri‐operative cardiac arrest as the 7th National Audit Project topic. The study was open to all UK hospitals offering anaesthetic services and had a three‐part design. First, baseline surveys of all anaesthetic departments and anaesthetists in the UK, examining respondents' prior peri‐operative cardiac arrest experience, resuscitation training and local departmental preparedness. Second, an activity survey to record anonymised details of all anaesthetic activity in each site over 4 days, enabling national estimates of annual anaesthetic activity, complexity and complication rates. Third, a case registry of all instances of peri‐operative cardiac arrest in the UK, reported confidentially and anonymously, over 1 year starting 16 June 2021, followed by expert review using a structured process to minimise bias. The definition of peri‐operative cardiac arrest was the delivery of five or more chest compressions and/or defibrillation in a patient having a procedure under the care of an anaesthetist. The peri‐operative period began with the World Health Organization ‘sign‐in’ checklist or first hands‐on contact with the patient and ended either 24 h after the patient handover (e.g. to the recovery room or intensive care unit) or at discharge if this occured earlier than 24 h. These components described the epidemiology of peri‐operative cardiac arrest in the UK and provide a basis for developing guidelines and interventional studies.

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          Identifying careless responses in survey data.

          When data are collected via anonymous Internet surveys, particularly under conditions of obligatory participation (such as with student samples), data quality can be a concern. However, little guidance exists in the published literature regarding techniques for detecting careless responses. Previously several potential approaches have been suggested for identifying careless respondents via indices computed from the data, yet almost no prior work has examined the relationships among these indicators or the types of data patterns identified by each. In 2 studies, we examined several methods for identifying careless responses, including (a) special items designed to detect careless response, (b) response consistency indices formed from responses to typical survey items, (c) multivariate outlier analysis, (d) response time, and (e) self-reported diligence. Results indicated that there are two distinct patterns of careless response (random and nonrandom) and that different indices are needed to identify these different response patterns. We also found that approximately 10%-12% of undergraduates completing a lengthy survey for course credit were identified as careless responders. In Study 2, we simulated data with known random response patterns to determine the efficacy of several indicators of careless response. We found that the nature of the data strongly influenced the efficacy of the indices to identify careless responses. Recommendations include using identified rather than anonymous responses, incorporating instructed response items before data collection, as well as computing consistency indices and multivariate outlier analysis to ensure high-quality data.
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            Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 1: anaesthesia.

            This project was devised to estimate the incidence of major complications of airway management during anaesthesia in the UK and to study these events. Reports of major airway management complications during anaesthesia (death, brain damage, emergency surgical airway, unanticipated intensive care unit admission) were collected from all National Health Service hospitals for 1 yr. An expert panel assessed inclusion criteria, outcome, and airway management. A matched concurrent census estimated a denominator of 2.9 million general anaesthetics annually. Of 184 reports meeting inclusion criteria, 133 related to general anaesthesia: 46 events per million general anaesthetics [95% confidence interval (CI) 38-54] or one per 22,000 (95% CI 1 per 26-18,000). Anaesthesia events led to 16 deaths and three episodes of persistent brain damage: a mortality rate of 5.6 per million general anaesthetics (95% CI 2.8-8.3): one per 180,000 (95% CI 1 per 352-120,000). These estimates assume that all such cases were captured. Rates of death and brain damage for different airway devices (facemask, supraglottic airway, tracheal tube) varied little. Airway management was considered good in 19% of assessable anaesthesia cases. Elements of care were judged poor in three-quarters: in only three deaths was airway management considered exclusively good. Although these data suggest the incidence of death and brain damage from airway management during general anaesthesia is low, statistical analysis of the distribution of reports suggests as few as 25% of relevant incidents may have been reported. It therefore provides an indication of the lower limit for incidence of such complications. The review of airway management indicates that in a majority of cases, there is 'room for improvement'.
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              European Resuscitation Council Guidelines 2021: Adult advanced life support

              These European Resuscitation Council Advanced Life Support guidelines, are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. This section provides guidelines on the prevention of and ALS treatments for both in-hospital cardiac arrest and out-of-hospital cardiac arrest.
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                Author and article information

                Contributors
                Role: Research Fellow, Specialty Registrar@adk300
                Role: Research Fellow, Academic Clinical Fellow@drrichstrong
                Role: Research Fellow, Specialty Registrar@emirakur
                Role: Consultant@doctimcook
                Role: Specialty Registrar
                Role: Research Team
                Role: Director, Professor@IainMoppett
                Role: Director, Professor@rmoonesinghe
                Role: Consultant@SeemaMosca
                Role: Consultant
                Role: Consultant
                Role: Consultant
                Role: Consultant@Simon_Finney
                Role: Professor
                Role: Consultant@noolslucas
                Role: Consultant
                Role: Consultant@RonelleMouton
                Role: Professor@JerryPNolan
                Role: Associate Professor@kalapappaj
                Role: Consultant
                Role: Consultant@katie_samuel_
                Role: NIHR Clinician Scientist@BarneyUoB
                Role: Consultant
                Role: Anaesthesia Associate@LeeVarney2000
                Role: Social Scientist, Senior Research Fellow@CeciliaVindrola
                Role: Researcher
                Role: Associate Specialist
                Role: Medical Director
                Role: Lecturer
                Role: Deputy Chief Executive Officer@skdrake
                Role: Research Team
                Role: Research Team
                Role: Consultantjasmeet.soar@nbt.nhs.uk , @jas_soar , @NAPs_RCoA
                Journal
                Anaesthesia
                Anaesthesia
                10.1111/(ISSN)1365-2044
                ANAE
                Anaesthesia
                John Wiley and Sons Inc. (Hoboken )
                0003-2409
                1365-2044
                16 September 2022
                December 2022
                : 77
                : 12 ( doiID: 10.1111/anae.v77.12 )
                : 1376-1385
                Author notes
                [*] [* ] Correspondence to: J. Soar

                Email: jasmeet.soar@ 123456nbt.nhs.uk

                [*]

                For full author affiliations, see Appendix 1

                Author information
                https://orcid.org/0000-0001-9488-4086
                https://orcid.org/0000-0001-9479-0143
                https://orcid.org/0000-0003-0864-3564
                https://orcid.org/0000-0002-3654-497X
                https://orcid.org/0000-0001-9057-497X
                https://orcid.org/0000-0003-3750-6067
                https://orcid.org/0000-0002-6730-5824
                https://orcid.org/0000-0002-9991-507X
                https://orcid.org/0000-0002-8179-6367
                https://orcid.org/0000-0003-0847-4297
                https://orcid.org/0000-0003-0315-5801
                https://orcid.org/0000-0001-8219-1952
                https://orcid.org/0000-0002-9789-1334
                https://orcid.org/0000-0001-8130-2067
                https://orcid.org/0000-0001-9562-8199
                https://orcid.org/0000-0003-3141-3812
                https://orcid.org/0000-0002-3559-0595
                https://orcid.org/0000-0001-8995-6583
                https://orcid.org/0000-0002-6198-4985
                https://orcid.org/0000-0002-0295-6773
                https://orcid.org/0000-0001-7859-1646
                https://orcid.org/0000-0002-4466-8374
                https://orcid.org/0000-0002-1836-289X
                https://orcid.org/0000-0002-1222-6483
                https://orcid.org/0000-0002-5249-8256
                https://orcid.org/0000-0003-0120-0365
                https://orcid.org/0000-0001-5970-6073
                Article
                ANAE15856 ANAE.2022.00627
                10.1111/anae.15856
                9826156
                36111390
                ca416b92-68a3-42dd-aea6-453fb580ae84
                © 2022 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

                History
                : 15 August 2022
                Page count
                Figures: 0, Tables: 2, Pages: 1385, Words: 7320
                Funding
                Funded by: Royal College of Anaesthetists , doi 10.13039/501100001297;
                Categories
                Original Article
                Original Articles
                Custom metadata
                2.0
                December 2022
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.2.3 mode:remove_FC converted:08.01.2023

                Anesthesiology & Pain management
                cardiac arrest,nap7,operating theatre,peri‐operative,resuscitation

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