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      Development of silver film coating on dental ti15mo alloy to enhance two-body wear resistance, biocompatibility and cytotoxicity effect

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          Abstract

          ABSTRACT The basic aim of this in vitro study was to investigate the effects of different silver deposition times on the two-body wear, antibacterial and cytotoxicity properties of silver ions on Ti15Mo alloy. The direct current (DC) magnetron sputtering technique was used to create silver films at different times (30, 45 and 60 minutes); the experimental setup was predetermined. The phase structures, cross-sectional morphology, surface roughness, two-body wear behavior, antibacterial and cytotoxicity properties of all specimens were researched in detail. The surfaces of all films showed a homogeneous distribution. It was observed that silver films enhanced the two-body wear resistance of Ti15Mo alloys. Furthermore, significant correlations were discovered between hardness, surface roughness and wear volume loss. Compared to Ti15Mo alloys, the antibacterial and cytotoxicity test results showed that silver films deposited 30 and 45 min had superior antibacterial and biocompatibility properties.

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          Most cited references35

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          Photo-Inspired Antibacterial Activity and Wound Healing Acceleration by Hydrogel Embedded with Ag/Ag@AgCl/ZnO Nanostructures.

          Ag/Ag@AgCl/ZnO hybrid nanostructures are embedded in a hydrogel by a simple two-step technique. The Ag/Ag@AgCl nanostructures are assembled in the hydrogel via ultraviolet light chemical reduction followed by incorporation of ZnO nanostructures by NaOH precipitation. The hydrogel accelerates wound healing and exhibits high antibacterial efficiency against both Escherichia coli and Staphylococcus aureus under visible light irradiation. The Ag/Ag@AgCl nanostructures enhance the photocatalytic and antibacterial activity of ZnO due to the enhancement of reactive oxygen species by visible light. This hydrogel system kills 95.95% of E. coli and 98.49% of S. aureus within 20 min upon exposure to simulated visible light, and rapid sterilization plays a crucial role in wound healing. In addition, this system provides controllable, sustained release of silver and zinc ions over a period of 21 days arising from the reversible swelling-shrinking transition of the hydrogel triggered by the changing pH value in the biological environment. About 90% Zn2+ release is observed in the acidic environment after 3 days, whereas only 10% Zn2+ release occurs in the neutral environment after 21 days. In vivo results show that release of Ag+ and Zn2+ stimulates the immune function to produce a large number of white blood cells and neutrophils (2-4 times more than the control), thereby producing the synergistic antibacterial effects and accelerated wound healing.
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            Design of Antibacterial Surfaces and Interfaces: Polyelectrolyte Multilayers as a Multifunctional Platform

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              Oral toxicity of silver ions, silver nanoparticles and colloidal silver--a review.

              Orally administered silver has been described to be absorbed in a range of 0.4-18% in mammals with a human value of 18%. Based on findings in animals, silver seems to be distributed to all of the organs investigated, with the highest levels being observed in the intestine and stomach. In the skin, silver induces a blue-grey discoloration termed argyria. Excretion occurs via the bile and urine. The following dose-dependent animal toxicity findings have been reported: death, weight loss, hypoactivity, altered neurotransmitter levels, altered liver enzymes, altered blood values, enlarged hearts and immunological effects. Substantial evidence exists suggesting that the effects induced by particulate silver are mediated via silver ions that are released from the particle surface. With the current data regarding toxicity and average human dietary exposure, a Margin of Safety calculation indicates at least a factor of five before a level of concern to the general population is reached.
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                Author and article information

                Journal
                rmat
                Matéria (Rio de Janeiro)
                Matéria (Rio J.)
                Laboratório de Hidrogênio, Coppe - Universidade Federal do Rio de Janeiro; em cooperação com a Associação Brasileira do Hidrogênio, ABH2 (Rio de Janeiro, RJ, Brazil )
                1517-7076
                2023
                : 28
                : 2
                : e20230044
                Affiliations
                [01] Erzurum orgnameAtaturk University orgdiv1Faculty of Engineering orgdiv2Department of Mechanical Engineering Turkey
                Article
                S1517-70762023000200202 S1517-7076(23)02800200202
                10.1590/1517-7076-rmat-2023-0044
                ca4e152f-c78d-437f-8543-6478b117e291

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 10 February 2023
                : 08 March 2023
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 35, Pages: 0
                Product

                SciELO Brazil

                Categories
                Articles

                Ti15Mo,Biocompatibility,Antibacterial property,Two-Body Wear,DC magnetron sputtering

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