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Seprase, a membrane-type serine protease, has different expression patterns in intestinal- and diffuse-type gastric cancer.
Kyoko Okada
1 ,
Wen-Tien Chen ,
Satoshi Iwasa ,
Xin Jin ,
Tetsu Yamane ,
Akishi Ooi ,
Masako Mitsumata
2003
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Abstract
Seprase is an integral membrane serine proteinase with gelatinase activity that may be involved in cancer invasion and metastasis. However, the pathophysiologic significance of its expression in gastric cancer tissue has not been fully elucidated.