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      Guidelines for the Antibiotic Use in Adults with Acute Upper Respiratory Tract Infections

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          Abstract

          These guidelines were developed as part of the 2016 Policy Research Servicing Project by the Korea Centers for Disease Control and Prevention. A multidisciplinary approach was taken to formulate this guideline to provide practical information about the diagnosis and treatment of adults with acute upper respiratory tract infection, with the ultimate aim to promote the appropriate use of antibiotics. The formulation of this guideline was based on a systematic literature review and analysis of the latest research findings to facilitate evidence-based practice, and focused on key questions to help clinicians obtain solutions to clinical questions that may arise during the care of a patient. These guidelines mainly cover the subjects on the assessment of antibiotic indications and appropriate selection of antibiotics for adult patients with acute pharyngotonsillitis or acute sinusitis.

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          The economic burden of non-influenza-related viral respiratory tract infection in the United States.

          Viral respiratory tract infection (VRTI) is the most common illness in humans. Despite the high incidence, the economic impact of non-influenza-related VRTI has not been rigorously explored. Our objectives were to obtain an updated incidence of non-influenza-related VRTI in the United States and to quantify the health care resource use (direct costs) and productivity losses (indirect costs) associated with these infections. A nationwide telephone survey of US households (N = 4051) was conducted between November 3, 2000, and February 12, 2001 to obtain a representative estimate of the self-reported incidence of non-influenza-related VRTI and related treatment patterns. Direct treatment costs measured included outpatient clinician encounters, use of over-the-counter and prescription drugs, and associated infectious complications of non-influenza-related VRTI. Absenteeism estimates for infected individuals and parents of infected children were extrapolated from National Health Interview Survey data. Of survey respondents, 72% reported a non-influenza-related VRTI within the past year. Respondents who experienced a self-reported non-influenza-related VRTI averaged 2.5 episodes annually. When these rates are extrapolated to the entire US population, approximately 500 million non-influenza-related VRTI episodes occur per year. Similarly, if the treatment patterns reported by the respondents are extended to the population, the total economic impact of non-influenza-related VRTI approaches $40 billion annually (direct costs, $17 billion per year; and indirect costs, $22.5 billion per year). Largely because of the high attack rate, non-influenza-related VRTI imposes a greater economic burden than many other clinical conditions. The pending availability of effective antiviral therapies warrants increased attention be paid to this common and expensive illness.
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            European Position Paper on Rhinosinusitis and Nasal Polyps 2012.

            The European Position Paper on Rhinosinusitis and Nasal Polyps 2012 is the update of similar evidence based position papers published in 2005 and 2007.The document contains chapters on definitions and classification, we now also proposed definitions for difficult to treat rhinosinusitis, control of disease and better definitions for rhinosinusitis in children. More emphasis is placed on the diagnosis and treatment of acute rhinosinusitis. Throughout the document the terms chronic rhinosinusitis without nasal polyps and chronic rhinosinusitis with nasal polyps are used to further point out differences in pathophysiology and treatment of these two entities. There are extensive chapters on epidemiology and predisposing factors, inflammatory mechanisms, (differential) diagnosis of facial pain, genetics, cystic fibrosis, aspirin exacerbated respiratory disease, immunodeficiencies, allergic fungal rhinosinusitis and the relationship between upper and lower airways. The chapters on paediatric acute and chronic rhinosinusitis are totally rewritten. Last but not least all available evidence for management of acute rhinosinusitis and chronic rhinosinusitis with or without nasal polyps in adults and children is analyzed and presented and management schemes based on the evidence are proposed.
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              Clinical practice guideline (update): adult sinusitis.

              This update of a 2007 guideline from the American Academy of Otolaryngology--Head and Neck Surgery Foundation provides evidence-based recommendations to manage adult rhinosinusitis, defined as symptomatic inflammation of the paranasal sinuses and nasal cavity. Changes from the prior guideline include a consumer added to the update group, evidence from 42 new systematic reviews, enhanced information on patient education and counseling, a new algorithm to clarify action statement relationships, expanded opportunities for watchful waiting (without antibiotic therapy) as initial therapy of acute bacterial rhinosinusitis (ABRS), and 3 new recommendations for managing chronic rhinosinusitis (CRS).
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                Author and article information

                Journal
                Infect Chemother
                Infect Chemother
                IC
                Infection & Chemotherapy
                The Korean Society of Infectious Diseases and Korean Society for Chemotherapy
                2093-2340
                2092-6448
                December 2017
                26 December 2017
                : 49
                : 4
                : 326-352
                Affiliations
                [1 ]Korean Society of Infectious Diseases, Seoul, Korea.
                [2 ]Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
                [3 ]Korean Society of Otorhinolaryngology-Head and Neck Surgery, Seoul, Korea.
                [4 ]Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea.
                [5 ]Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University hospital Seoul, Seoul, Korea.
                [6 ]Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Seoul, Korea.
                [7 ]Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
                [8 ]Department of Otorhinolaryngology, Ajou University, School of Medicine, Suwon, Korea.
                [9 ]Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University, College of Medicine, Seoul, Korea.
                [10 ]Korean Association of Otorhinolaryngologists, Seoul, Korea.
                [11 ]Korean Association of Family Medicine, Seoul, Korea.
                [12 ]Department of Family Medicine, Myongji Hospital, Seonam University, College of Medicine, Goyang, Korea.
                [13 ]Korean Medical Practitioners Association, Seoul, Korea.
                [14 ]Department of Internal Medicine, Nammoon Medical Clinic, Seoul, Korea.
                [15 ]Division of Healthcare Technology Assessment Research, National Evidence-Based Healthcare Collaborating Agency, Seoul, Korea.
                [16 ]Korean Society for Chemotherapy, Seoul, Korea.
                [17 ]Department of Internal Medicine, Kungpook National University, School of Medicine, Daegu, Korea.
                Author notes
                Address correspondence to: Shin Woo Kim, MD, PhD. Division of Infectious Diseases, Department of Internal Medicine, Kyungpook National University Hospital, 130 Dongdoek-ro, Jung-gu, Daegu 41944, Korea. Tel: +82-53-200-6525, Fax: +82-53-426-2046, ksw2kms@ 123456knu.ac.kr
                Author information
                https://orcid.org/0000-0001-8435-935X
                https://orcid.org/0000-0002-3755-8249
                Article
                10.3947/ic.2017.49.4.326
                5754344
                29299900
                cc508acc-fb04-4e2e-be58-7c251006dfdb
                Copyright © 2017 by The Korean Society of Infectious Diseases and Korean Society for Chemotherapy

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 16 November 2017
                Funding
                Funded by: Korea Centers for Disease Control and Prevention, CrossRef http://dx.doi.org/10.13039/501100003669;
                Award ID: 2016-E23006-06
                Categories
                Special Article

                guideline,antibiotics,pharyngitis,tonsillitis,rhinosinusitis

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