Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors

Leysen, J.E.; Awouters, F; Kennis, L.; Laduron, P.M.; Vandenberk, J.; Janssen, P.A.J.

doi:10.1016/0024-3205(81)90747-5

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Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors

Author(s): J.E. Leysen , F. Awouters , L. Kennis , P.M. Laduron , J. Vandenberk , P.A.J. Janssen

Publication date Created: March 1981

Publication date (Print): March 1981

Journal: Life Sciences

Publisher: Elsevier BV

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Opiate receptor: demonstration in nervous tissue.

C Pert, S. Snyder (1973)

Tritiated naloxone, a powerful opiate antagonist, specifically binds to an opiate receptor of mammalian brain and guinea pig intestine. Competition for the opiate receptor by various opiates and their antagonists closely parallels their pharmacological potency. The opiate receptor is confined to nervous tissue.