Expression of orphan nuclear receptor NR4A2 in gastric cancer cells confers chemoresistance and predicts an unfavorable postoperative survival of gastric cancer patients with chemotherapy.

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Abstract

NR4A2, an orphan nuclear receptor essential in the generation of dopaminergic neurons, has been recently linked to inflammation and cancer. This study sought to identify the role of NR4A2 on chemoresistance and postoperative prognosis of gastric cancer (GC).

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Author and article information

Journal

Journal ID (iso-abbrev): Cancer

Title: Cancer

Publisher: Wiley

ISSN (Electronic): 1097-0142

ISSN (Print): 0008-543X

Publication date (Electronic): Oct 01 2013

Volume: 119

Issue: 19

Affiliations

[1 ] Department of Epidemiology, Second Military Medical University, Shanghai, China.

Article

DOI: 10.1002/cncr.28228

PubMed ID: 23821160

SO-VID: ce01ffc5-c8b4-4cc6-a8aa-e805d0c98148

History

Keywords: NR4A2,chemoresistance,gastric cancer,prognosis,surgery

Data availability:

Keywords: NR4A2, chemoresistance, gastric cancer, prognosis, surgery

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