29
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Comment on: Cut and paste: A novel method of re-attaching rectus muscles with cyanoacrylate during recessions in strabismus

      letter
      ,
      Indian Journal of Ophthalmology
      Medknow Publications

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Dear Editor, We are grateful for the interest shown by the authors in our article,[1 2] and the issues raised by them. The patients were blinded to the procedure, being unaware which eye had been randomized to conventional surgery and which to cyanoacrylate. We are aware of the importance of the assessor being blinded too, but due to logistic constraints could not carry it out in the majority of the cases. This issue has been raised before, and we too feel that the ‘backup’ Vicryl suture, which would have bound the capsule to the muscle-tendon complex, possibly helped us avoid a slipped muscle. We sutured the conjunctiva with 8-0 Vicryl. The authors’ point is valid: we did consider using fibrin glue in our cases, but the cost precluded us from doing so. The ideal would have been to stick both the muscle and the conjunctiva. We needed to have a ‘safety net’ in case of muscle slippage, and so we had designed our study to include a ‘backup’ 6-0 Vicryl suture: this had to be accessible to be of use and was allowed to be attached temporarily to the forehead, for about 4-6 h postoperatively. We did not come across any patient who had additional discomfort on account of this. Under topical anesthesia and with slight traction on the suture, such that it removed any slack, the suture was cut flush with the conjunctiva after gently pushing the latter back with the spring scissors. Since prior explanation had been provided to the patients, none appeared to be discomfited by this. We had not included cauterization in our protocol and avoided deviating from it. We staunched the bleeding by pressure before applying the cyanoacrylate. Even we have concluded that cautery of the detached muscle would be both helpful and save time. Whether a five minute delay is significant or not is a subjective matter. Normally, we too use the same Vicryl suture to reattach muscles in the same patient in a standard manner. We were trying to assess how well the muscle holds with glue and what kind of tissue reaction occurs to it. The six-month information on ocular movements was to convey to the reader that the muscles were holding well to their points of attachments. There was nothing to suggest any reaction to the glue. We understand that any novel approach need not necessarily prove better than the existing procedure. But when such a possibility is likely, one should explore that possibility. We do not claim that gluing a muscle back should, at least at this point in time, replace the standard procedure of suturing it, but that it can be done, and successfully so has been demonstrated by our study. What is its future, only time will tell.

          Related collections

          Most cited references2

          • Record: found
          • Abstract: found
          • Article: found
          Is Open Access

          Cut and paste: A novel method of re-attaching rectus muscles with cyanoacrylate during recessions in strabismus

          Aim: Bio-adhesives like cyanoacrylate offer an alternative to sutures to attach tissues, including in ophthalmology. This prospective trial evaluated the suitability and bio-tolerance of iso-amyl cyanoacrylate in rectus muscle recession surgery for strabismus. Materials and Methods: We randomized one eye in each of 10 cases of bilateral horizontal rectus recessions to 6/0 polyglactin and the other to iso-amyl-cyanoacrylate. We compared time to reattachment (from disinsertion), complications and inflammatory scores (0 to +3: nil, mild, moderate and severe) on Day One, at two and at four to six weeks post surgery. Results: There were no significant group differences in inflammatory scores (Wilcoxon, all values of P>0.05). All attachments held firm. Gluing took significantly longer by 5.24±1.91 min (95% CI for difference: 3.87-6.61). There were no complications. Conclusion: We feel that although it takes marginally longer, iso-amyl cyanoacrylate offers an effective and safe alternative to sutures for muscle recession in strabismus surgery. Since it is cheaper (vs. polyglactin) and offers multi-use possibility it may also prove to be cost-effective.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: found
            Is Open Access

            Cut and paste: A novel method of reattaching rectus muscles with cyanoacrylate during recessions in strabismus

            Dear Editor, We read with interest the article by Darakshan et al., titled “Cut and paste: A novel method of reattaching rectus muscles with cyanoacrylate during recessions in strabismus”.[1] We wish to make the following comments: Were the patients and the examiners blinded to the procedure performed in individual eyes? If not they are likely to induce bias in the observations. During recession surgeries it is attempted to keep the muscle capsule intact to prevent injury to the muscle belly and subsequent bleeding.[2] The muscle capsule is impervious to cyanoacrylate glue, which can be verified by simply applying the glue to a dissected muscle capsule from a resected muscle stump and observing the other surface for adhesiveness. The muscle tendon gets exposed when it is detached from its insertion and would provide a limited surface area for glue application and have a limited holding strength. We have not attempted to attach a muscle with glue after making this observation. The muscle in our opinion would have a definite possibility of slippage within its capsule.[2] The authors have probably escaped this complication by using their “backup” option of vicryl which kept the recessed muscle in place for a sufficient duration to provide some adhesions. In spite of this they were probably lucky to avoid muscle slippage. It is not clear whether they sutured the conjunctiva or glued it in the eyes in which they used the glue for muscle attachment. What would be the point in suturing the conjunctiva as inflammation and patient discomfort are primarily because of the conjunctival sutures in strabismus surgery?[2] How could they be justified in using a vicryl suture coming out of the conjunctival incision and attaching it to the forehead? This extreme patient discomfort was not accounted for in the analysis. Moreover, they do not talk about how the conjunctiva was approximated after this suture was removed. Was there any need for suturing or reapplication of glue? What about the patient discomfort due to this? It is stated that cauterization was not a part of the protocol. One would be rather adventurous to use cyanoacrylate in a bleeding muscle. Why was cautery not used prior to muscle attachment? In our opinion a five-minute delay per muscle in our overworked operation theaters is significant. We have been using the same vicryl suture for both the eyes of the same patient according to a standard procedure.[3] It reduces the cost of sutures to half. It is well-documented that cyanoacrylate forms a solid, impermeable mass in situ and this persists as a foreign body causing inflammatory reactions.[4] The authors talk about ocular movements at six months’ follow-up whereas the main concern at six months should be reaction to this foreign body. If movements are satisfactory at four weeks we do not expect a change at six months because the muscle has firmly attached by four weeks to its new insertion. Previous researchers have attempted to use glue in faden procedure and that too with limited success.[5] The process being more time-consuming does not seem to offer any advantage. There is a definite possibility of muscle slippage and the benefits being attributed to the procedure are probably due to bias. Tissue glue is successfully used when a non-mechanically strained tissue like conjunctiva needs attachment but attempting to attach a muscle would be ambitious and using it for resections as suggested by the authors could be disastrous. The overall advantage of cyanoacrylate glue over conventional sutures for muscle attachment in terms of scientific plausibility and the need for change remains questionable.
              Bookmark

              Author and article information

              Journal
              Indian J Ophthalmol
              IJO
              Indian Journal of Ophthalmology
              Medknow Publications (India )
              0301-4738
              1998-3689
              Nov-Dec 2011
              : 59
              : 6
              : 524-525
              Affiliations
              [1]Institute of Ophthalmology, JN Medical College, Aligarh Muslim University, Aligarh, UP, India
              Author notes
              Correspondence to: Dr. A K Amitava, Institute of Ophthalmology, 4/758, Taban Cottage, Friends Colony, Dodhpur, Aligarh-202 001, India. E-mail: akamitava@ 123456gmail.com
              Article
              IJO-59-524
              10.4103/0301-4738.86336
              3214437
              22011509
              cee4f2f4-71af-4dab-806c-8211df0a265e
              Copyright: © Indian Journal of Ophthalmology

              This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

              History
              Categories
              Letters to the Editor

              Ophthalmology & Optometry
              Ophthalmology & Optometry

              Comments

              Comment on this article