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      Role of 99mTc-methylene diphosphonate bone scan in the evaluation of the viability of the bone flap in mandibular reconstruction in patients with oromaxillofacial malignancies

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          Abstract

          Osteo-cutaneous flap are commonly used for reconstruction of bone defect after oncology surgery. The success of surgery depends on the viability of the bone flap. Bone scan is a known, but less performed method, to look for viability of bone flaps. We describe a case of 50-year-old lady, presenting with squamous cell carcinoma of left buccal mucosa (cT4N1M0) involving the skin and mandible. She underwent left segmental mandibulectomy and upper alveolectomy with neck dissection, followed by reconstruction using a fibular osteo-cutaneous flap and anterolateral thigh free flap. On postoperative day 10, the intraoral flap showed signs of nonviability. The patient was sent to nuclear medicine for assessment of viability of the free fibula flap. The patient underwent three phase 99mTc-methylene diphosphonate (MDP) bone scan and single-photon emission computerized tomography. Computerized tomography showing good tracer uptake in fibula confirming viability. The case reflects the use of 99mTc-MDP in viability assessment of the bone flap.

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          Most cited references12

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          Fibula free flap mandibular reconstruction.

          D Hidalgo (1993)
          The fibula free flap is rapidly becoming the donor site of choice for mandibular reconstruction. Its versatility makes it suitable for the majority of composite mandibular defects. The indications, operative techniques, and postoperative considerations are detailed in this article. Important principles of preoperative preparation, flap design, graft shaping, and bone fixation are included.
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            Three-phase bone scintigraphy and viability of vascularized bone grafts for mandibular reconstruction.

            Three-phase bone scintigraphy was undertaken to check the anastomotic patency and monitor the viability of vascularized bone grafts. Ten consecutive patients who underwent vascularized bone grafting of the mandible were reviewed. A successful clinical outcome was achieved in 8 patients. The graft failed in 2 patients. In this series, 3-phase bone scintigraphy of radiolabeled (99m)Tc-methylene-diphosphonate was performed at 7 days, and at 1, 3, 6, and 12 months after reconstruction. Assessments made using 3-phase bone images were compared with the clinical findings. The clinical outcome of the cases presented in our series correlated extremely well with 3-phase bone images. Three-phase bone scintigraphy is a useful method for the assessment of patency and viability of vascularized bone grafts. The use of this method can be very helpful in assessing the anastomotic patency and viability of a graft which for clinical reasons is suspected of being non-viable.
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              The vascularized fibular flap for mandibular reconstruction.

              Vascularized fibular bone grafts have advantages over other bone grafts in the restoration of the contour and function of defective mandibles. The fibular graft can be tailored to fit even major mandibular defects; in combination with preformed temporomandibular joint prostheses total mandibular reconstruction can be performed in a single procedure. The fibular transplant is considered ideal for the insertion of implants to support dental suprastructures to obtain maximal oral rehabilitation. We have used fibular grafts in eight cases for primary or secondary reconstruction of a variety of mandibular defects resulting from cancer, chronic osteomyelitis or gunshot injuries. The results have been most encouraging with respect to function and cosmetic appearance. There have been no transplant failures and minimal donor site complications.
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                Author and article information

                Journal
                Indian J Nucl Med
                Indian J Nucl Med
                IJNM
                Indian Journal of Nuclear Medicine : IJNM : The Official Journal of the Society of Nuclear Medicine, India
                Medknow Publications & Media Pvt Ltd (India )
                0972-3919
                0974-0244
                Jul-Sep 2015
                : 30
                : 3
                : 280-282
                Affiliations
                [1]Department of Nuclear Medicine, JIPMER, Puducherry, India
                [1 ]Department of Surgical Oncology, JIPMER, Puducherry, India
                [2 ]Department of Plastic Surgery, JIPMER, Puducherry, India
                Author notes
                Address for correspondence: Dr. Prasanth Penumadu, Department of Surgical Oncology, JIPMER, Puducherry, India. E-mail: prasanth.p@ 123456jipmer.edu.in
                Article
                IJNM-30-280
                10.4103/0972-3919.158549
                4479925
                cf210e31-8a06-43ec-8a24-b507c9a8d621
                Copyright: © Indian Journal of Nuclear Medicine

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Categories
                Case Report

                Radiology & Imaging
                99mtc-methylene diphosphonate,bone scan,fibular graft,osteo-cutaneous flap,viability

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