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      Comparison of Perioperative and Postoperative Outcomes Among 3 Left Atrial Incisions: Conventional Direct, Transseptal, and Superior Septal Left Atriotomy

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          Abstract

          Background:

          Achieving optimal exposure of the mitral valve during surgical intervention poses a significant challenge. This study aimed to compare perioperative and postoperative outcomes associated with 3 left atriotomy techniques in mitral valve surgery—the conventional direct, transseptal, and superior septal approaches—and assess differences during the surgical procedure and the postoperative period.

          Methods:

          Inclusion criteria were patients undergoing mitral valve surgery from January 2010 to December 2020, categorized into 3 cohorts: group 1 (conventional direct; n = 115), group 2 (transseptal; n = 33), and group 3 (superior septal; n = 59). To bolster sample size, the study included patients undergoing mitral valve surgery independently or in conjunction with other procedures (eg, coronary artery bypass grafting, aortictricuspid surgery, or maze procedure).

          Results:

          No substantial variance was observed in the etiology of mitral valve disease across groups, except for a higher incidence of endocarditis in group 3 ( P = .01). Group 1 exhibited a higher frequency of elective surgeries and isolated mitral valve procedures ( P = .008), along with reduced aortic clamping and cardiopulmonary bypass durations ( P = .002). Conversely, group 3 patients represented a greater proportion of emergency procedures ( P = .01) and prolonged intensive care unit and hospital stays ( P = .001). No significant disparities were detected in terms of permanent pacemaker implantation, postoperative complications, or mortality among the groups.

          Conclusion:

          Mitral valve operations that employed these 3 atriotomy techniques demonstrated a safe profile. The conventional direct approach notably reduced aortic clamping and cardiopulmonary bypass durations. The superior septal method was primarily employed for acute pathologies, with no significant escalation in postoperative arrhythmias or permanent pacemaker implantation, although these patients had prolonged intensive care unit and hospital stays. These outcomes may be linked to the underlying pathology and nature of the surgical intervention rather than the incision method itself.

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          Most cited references21

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          Epidemiology of valvular heart disease in the adult.

          Valvular heart disease remains common in industrialized countries, because the decrease in prevalence of rheumatic heart diseases has been accompanied by an increase in that of degenerative valve diseases. Aortic stenosis and mitral regurgitation are the two most common types of valvular disease in Europe. The prevalence of valvular disease increases sharply with age, owing to the predominance of degenerative etiologies. The burden of heart valve disease in the elderly has an important impact on patient management, given the high frequency of comorbidity and the increased risk associated with intervention in this age group. Endocarditis is an important etiology of valvular disease and is most commonly caused by Staphylococci. Rheumatic heart disease remains prevalent in developing countries.
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            Fifty years of open-heart surgery.

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              Superior transseptal approach to mitral valve is associated with a higher need for pacemaker implantation than the left atrial approach.

              Several studies suggest that the superior transseptal approach to mitral valve surgery leads to sinus node dysfunction. The clinical consequences are not known. Consecutive patients undergoing surgery for mitral valve disease from November 16, 1994 through January 26, 2004 were retrospectively evaluated. The surgeons used either the superior transseptal (group A) or left atrial approach (group B). The risk of pacemaker implantation associated with the superior transseptal approach as compared with the left atrial approach was estimated using the multivariate Cox regression analysis to adjust for possible confounders. We included 577 patients, 150 in group A and 427 in group B. Forty-four patients had a pacemaker implanted after the surgery; 17 in group A and 27 in group B (p = 0.010). The superior transseptal approach was an independent risk factor of pacemaker implantation in multivariate analysis (hazard ratio 2.2 [1.2 to 4.1], p = 0.014). Nineteen patients had a pacemaker implanted because of sinus node dysfunction; 9 in group A and 10 in group B (p = 0.017). Group A was an independent predictor of pacemaker implantation because of sinus node dysfunction in bivariate analyses. The risk of pacemaker implantation because of atrioventricular conduction disturbances was not different between the groups (p = 0.178). The superior transseptal approach has a higher risk of clinically significant sinus node dysfunction than the left atrial approach.
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                Author and article information

                Journal
                Tex Heart Inst J
                Tex Heart Inst J
                thij
                The Texas Heart Institute Journal
                Texas Heart® Institute, Houston
                0730-2347
                1526-6702
                Jan-Jun 2024
                31 January 2024
                : 51
                : 1
                : e238162
                Affiliations
                [1 ]Division of Cardiovascular Surgery, Department of Surgery, University Hospitals of Geneva, Geneva, Switzerland
                [2 ]Division of Medical Specialties, University Hospitals of Geneva, Geneva, Switzerland
                Author notes
                Corresponding author: Estelle Démoulin, 134 Chemin de la Montagne, 1224 Chêne-Bougeries, Switzerland ( demoulinestelle@ 123456gmail.com )

                Author Contributions: Estelle Démoulin contributed to the acquisition of data and drafting of the manuscript. Mustafa Cikirikcioglu and Estelle Démoulin contributed to the concept and design and drafting of the manuscript. Dionysios Adamopoulos and Estelle Démoulin contributed to the analysis and interpretation of data and statistical analysis. Tornike Sologashvili, Mathieu van Steenberghe, Jalal Jolou, Haran Burri, and Christoph Huber contributed to the concept and design and drafting of the manuscript.

                Article
                10.14503/THIJ-23-8162
                11075488
                38291909
                d066cdaf-9a2e-4e38-87b3-6bea9f79ff4b
                © 2024 The Authors. Published by The Texas Heart Institute ®

                This is an Open Access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use and distribution in any medium, provided the original work is properly cited, and the use is noncommercial.

                History
                Page count
                Pages: 7
                Categories
                Clinical Investigation

                mitral valve,perioperative period,complications,artificial pacemaker

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